Results 71 to 80 of about 3,127,636 (279)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Advanced ScienceInterfacial instability between different electrolyte materials is a critical challenge hindering the commercialization of CO2 electrolysis via solid oxide electrolysis cells (SOECs).
Rustam Yuldashev +4 more
doaj +1 more source
Frontiers in Energy Research, 2019 This present study aims in understanding the influence of dominant fatty acid esters of waste animal fat biodiesel on its emission characteristics in CI engine.
Ranjitha Jambulingam +4 more
doaj +1 more source
CO2 as Resource. Society’s Willingness to Pay Analysis
Environmental and Climate Technologies, 2022 Climate change, including the efficient management of CO2 emissions, is considered a significant environmental challenge today. Carbon dioxide is still considered an undesirable by-product that must be eliminated.
Terjanika Viktorija +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
CO2 leakage can cause loss of benthic biodiversity in submarine sands [PDF]
, 2019 One of the options to mitigate atmospheric CO2 increase is CO2 Capture and Storage in sub-seabed geological formations. Since predicting long-term storage security is difficult, different CO2 leakage scenarios and impacts on marine ecosystems require ...
Guilini, Katja +4 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Summer CO2 evasion from streams and rivers in the Kolyma River basin, north-east Siberia [PDF]
, 2013 Inland water systems are generally supersaturated in carbon dioxide (CO2) and are increasingly recognized as playing an important role in the global carbon cycle.
Alin S.R +50 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Facile and controllable synthesis of BaCO3 crystals superstructures using a CO2-storage material
Green Energy & Environment, 2017 We here report a new CO2 capture and storage method that converts CO2 into a novel alkyl carbonate salt, denoted as CO2SM, by a system consisting of equimolar 1,4-butanediol (BDO) and 1,2-ethylenediamine (EDA).
Feng Sha +7 more
doaj +1 more source