Results 71 to 80 of about 4,064,010 (293)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Revolutionary advancements in carbon dioxide valorization via metal-organic framework-based strategies

Carbon Capture Science & Technology
The conversion of CO2 to value-added chemicals garners considerable attention because it produces renewable hydrocarbon fuels for use in the chemical industry and simultaneously reduces the atmospheric CO2 concentration to mitigate the effects of global ...
Sheraz Ahmed, Muhammad Kashif Khan, Jaehoon Kim   +2 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Recent advancements in integrating CO2 capture from flue gas and ambient air with thermal catalytic conversion for efficient CO2 utilization

Journal of CO2 Utilization
Capturing CO2 and converting it into valuable chemicals and fuels have been regarded as a pivotal strategy in addressing the environmental challenges of ever-growing CO2 emissions.
Ruoyu Zhang, Zhenwei Xie, Qingfeng Ge, Xinli Zhu   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Recent progress in microporous membrane reactors for catalytic conversion CO2 into value-added chemicals

Advanced Membranes
Catalytic conversion of CO2 into high value-added chemicals offers an attractive route to address a range of climate issues caused by excessive CO2 emission. However, the chemical inertness of CO2 generally leads to unsatisfied CO2 conversion and product
Zhangjun Dai, Pei Nian, Longtian Cao, Xiaolong Wang, Xinhua Gao, Wenlan Ji, Yibin Wei   +6 more
doaj   +1 more source

Facile synthesis of MoS2/Cu as trifunctional catalyst for electrochemical overall water splitting and photocatalytic CO2 conversion

, 2021
Water splitting and CO2 conversion are emerging energy transfer techniques to generate hydrogen and low carbon fuel as eco-friendly energy sources. Herein, a frugal and facile approach for decorating MoS2 nanosheets on copper nanorods to design MoS2/Cu ...
Tayiba Ilyas, F. Raziq, Sharafat Ali, A. Zada, Nasir Ilyas, Rahim Shaha, Yong Wang, Liang Qiao   +7 more
semanticscholar   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Recent Progress and Novel Applications in Enzymatic Conversion of Carbon Dioxide

Energies, 2017
Turning carbon dioxide (CO2) into fuels and chemicals using chemical, photochemical, electrochemical, and enzymatic methods could be used to recycle large quantities of carbon.
Nguyen Van Duc Long, Jintae Lee, Kee-Kahb Koo, Patricia Luis, Moonyong Lee   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source