Results 21 to 30 of about 12,478 (266)

Toward carbon neutrality: A comprehensive review of CO2 hydrogenation to olefins and aromatics

Resources Chemicals and Materials
The catalytic hydrogenation of carbon dioxide (CO2) into high‐value chemicals offers a sustainable approach to reduce greenhouse gas emissions and dependence on fossil resources.
Jianxiang Han, Xiwen Cui, Jian Sun
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Carbon-based material for CO2 catalytic conversion applications

Carbon Future
Carbon dioxide (CO2) is not only a greenhouse gas but also an abundant carbon resource. CO2 hydrogenation from electrocatalysis and thermocatalysis to high-value-added chemicals has attracted wide attention.
Wenhang Wang, Yang Wang, Xiangjin Kong, Hui Ning, Mingbo Wu   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Similarities and Differences Between CO2 Reduction and Electro‐Hydrogenation of Organic Carbonyls with Fe Porphyrins: A Case Study

ChemElectroChem
Iron porphyrins are well established for CO2 reduction, the electro‐hydrogenation of a CO bond in CO2, which can proceed via metal‐hydride formation (H+ reduction) or direct CO2 reduction by Fe0 with subsequent protonation.
Tianyin Huang, Yang Lyu, Junhong Chen, Dominik P. Halter   +3 more
doaj   +1 more source

CO2 Hydrogenation on Metal-Organic Frameworks-Based Catalysts: A Mini Review

Frontiers in Chemistry, 2022
Conversion of carbon dioxide (CO2) into value-added fuels and chemicals can not only reduce the emission amount of CO2 in the atmosphere and alleviate the greenhouse effect but also realize carbon recycling. Through hydrogenation with renewable hydrogen (
Qian Zhang, Qian Zhang, Sen Wang, Mei Dong, Weibin Fan   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

C–C bond coupling with sp3 C–H bond via active intermediates from CO2 hydrogenation

Nature Communications
Compared to the sluggish kinetics observed in methanol-mediated side-chain alkylation of methyl groups with sp3 C–H bonds, CO2 hydrogenation emerges as a sustainable alternative strategy, yet it remains a challenge.
Qianli Ma, Jianian Cheng, Xiaojing Wu, Jin Xie, Ruihui Zhang, Zhihe Mao, Hongfang Yang, Wenjun Fan, Jianrong Zeng, Johannes Hendrik Bitter, Guanna Li, Zelong Li, Can Li   +12 more
doaj   +1 more source

CO2 hydrogenation to value-added chemicals over mesoporous carbon-supported Trimetallic NiGaAg catalysts

Sustainable Chemistry for Climate Action
Hydrogenation of CO2 is an important and useful reaction, both from the perspective of CO2 mitigation and the added value to the products such as formaldehyde and methanol.
Iman Abdullah, Aulia Oktaviani, Patrik Chandra, Wipark Anutrasakda, Yuni Krisyuningsih Krisnandi   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source