Results 51 to 60 of about 644,330 (242)
Ultrasonics SonochemistryHydrodynamic cavitation (HC) surge accompanied by strong swirl is widely present in fluid machinery and has become a hot topic in many engineering fields. This paper employed a two-way coupling Eulerian-Lagrangian multiscale cavitation modeling method to
Ziyang Wang +3 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Estimated CO2 Emissions and Analysis of Solid Recovered Fuel (SRF) as an Alternative Fuel
Asian Journal of Atmospheric Environment, 2013 The purpose of this study was to develop a CO2 emission factor for refuse plastic fuel (RPF) combustion facilities, and calculate the CO2 emissions from these facilities.
Sang-Kyun Kim +4 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Demonstration of high biomass ratio co-firing at existing coal fired boiler
Nihon Kikai Gakkai ronbunshu, 2017 There is a CO2 emission reduction method of burning woody biomass and coal, as a technical method to reduce the CO2 emission of the coal fired power plant. But a co-firing woody biomass ratio of the existing coal fired power plants gives only the 2-3% co-
Hitoshi FUKUSHIMA +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Integrating Stamping Tool Temperature Effects into Early-Stage Process Design: Insights from an Industrial Benchmark [PDF]
MATEC Web of ConferencesReducing the CO2 footprint has become a key objective in the manufacturing sector, with the automotive industry being no exception. A significant portion of a car body consists of stamped components, making the reduction of CO2 emissions in stamping ...
Insausti Lide +5 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source