Results 101 to 110 of about 589,687 (293)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Numerical modeling of CO2 separation process
Archives of Thermodynamics, 2013 Abstract Paper presents the results of numerical modelling of a rectangular tube filled with a mixture of air and CO2 by means of the induced standing wave. Assumed frequency inducing the acoustic waves corresponds to the frequency of the thermoacoustic engine. In order to reduce the computational time the engine has been replaced by the mechanical
Leszek Remiorz +2 more
openaire +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Polymeric Membrane for CO2/CH4 Separation [PDF]
, 2021 This chapter presents a critical overview of polymeric membrane applications for CO2/CH4 separation. Comparative summary of availability and practice of different gas separation methods are outlined to give a state-of-the-art view of this technology.
openaire +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Thermal analysis, optimization and design of a Martian oxygen production plant [PDF]
The objective is to optimally design the thermal components of a system that uses carbon dioxide (CO2) from the Martian atmosphere to produce oxygen (O2) for spacecraft propulsion and/or life-support.
Iyer, Venkatesh A., Sridhar, K. R.
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
, 2018 Highly flexible nanoporous materials, exhibiting for instance gate opening or breathing behavior, are often presented as candidates for separation processes due to their supposed high adsorption selectivity.
Boutin, Anne +3 more
core +3 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
A blackbody-pumped CO2-N2 transfer laser [PDF]
A compact blackbody-pumped CO2-N2 transfer laser was constructed and the significant operating parameters were investigated. Lasing was achieved at 10.6 microns by passing preheated N2 through a 1.5-mm-diameter nozzle to a laser cavity where the N2 was ...
Deyoung, R. J., Higdon, N. S.
core +1 more source