Results 31 to 40 of about 175,533 (262)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

A preliminary assessment of geological CO2 storage in the Khorat Plateau, Thailand

open access: yesFrontiers in Energy Research, 2022
The main carbon dioxide (CO2) emissions in Thailand come from the energy sector. Gas-based power plants, including natural gas and biogas, are CO2 point sources, and are mostly located in the Khorat Plateau. Geological CO2 storage is an important element
Piyaphong Chenrai   +8 more
doaj   +1 more source

Monitoring Subsurface CO2Storage [PDF]

open access: yesOil & Gas Science and Technology, 2005
An overview is given of various currently applied monitoring techniques for CO2 storage. Techniques are subdivided in correspondence to their applicability for monitoring three distinct realms. These are: - the atmosphere and the near- surface; - the overburden (including faults and wells); - the reservoir with its seals.
Winthaegen, P., Arts, R., Schroot, B.M.
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Assessment of CO2 EOR and its geo-storage potential in mature oil reservoirs, Shengli Oilfield, China

open access: yesPetroleum Exploration and Development, 2009
Most oil reservoirs in the Shengli Oilfield area have entered middle and late development stages after nearly 40-years of production, and they are suitable for applying CO2 EOR and carbon storage techniques. This study is aimed at assessing the potential
Zhang Liang   +4 more
doaj   +1 more source

A study of the potential of field-scale of CO2 geological storage and enhanced water recovery in the eastern Junggar area of Xinjiang

open access: yesShuiwen dizhi gongcheng dizhi, 2021
CO2 geological storage combined with saline recovery (CO2-EWR) is considered to be one of the effective storage methods. Taking the lead in carrying out CO2-EWR technology in the eastern Junggar of Xinjiang can achieve CO2 emission reduction and mean ...
Xin MA   +7 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

An Integrated Framework for Geothermal Energy Storage with CO2 Sequestration and Utilization

open access: yesEngineering, 2023
Subsurface geothermal energy storage has greater potential than other energy storage strategies in terms of capacity scale and time duration. Carbon dioxide (CO2) is regarded as a potential medium for energy storage due to its superior thermal properties.
Yueliang Liu   +9 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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