Results 51 to 60 of about 7,836,779 (233)

Performance Comparisons of Youth Weightlifters as a Function of Age Group and Sex

Journal of Functional Morphology and Kinesiology, 2021
This study was designed to provide an overview of weightlifting performance as a function of age group and sex and evaluate the potential of countermovement jump height (CMJH) as a tool to gauge performance potential. Data from 130 youth athletes (female,
Satoshi Mizuguchi, Aaron J. Cunanan, Dylan G. Suarez, William E. Cedar, Mark A. South, Daniel Gahreman, William G. Hornsby, Michael H. Stone   +7 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Associations between physical activity and health-related quality of life in cancer patients on active treatment

Biomedical Human Kinetics
The aim of this study is to determine the physical activity levels of patients undergoing active cancer treatment and to examine the relationship between physical activity and quality of life.
Bolukbas Merve Gezen, Vatansever Serife, Sonmez Deniz Zeynep   +2 more
doaj   +1 more source

“You Know, Coaching, It Feels Like a Bit of a Magpie Game’’: A Qualitative Investigation into Sources of Teacher-Coach Knowledge and the Subsequent Impact on Espoused Teacher-Coach Pedagogy

Education Sciences
The sources of knowledge that sport coaches use have been widely researched however, their impact on espoused pedagogy in the teacher-coach context is comparatively underexplored The purpose of this study was to explore how teacher-coaches view knowledge,
Jack Emmerson, Stephen Macdonald
doaj   +1 more source

Comparison of the Relationship between Lying and Standing Ultrasonography Measures of Muscle Morphology with Isometric and Dynamic Force Production Capabilities

Sports, 2017
The purpose of the current study was (1) to examine the differences between standing and lying measures of vastus lateralis (VL), muscle thickness (MT), pennation angle (PA), and cross-sectional area (CSA) using ultrasonography; and (2) to explore the ...
John P. Wagle, Kevin M. Carroll, Aaron J. Cunanan, Christopher B. Taber, Alexander Wetmore, Garett E. Bingham, Brad H. DeWeese, Kimitake Sato, Charles A. Stuart, Michael H. Stone   +9 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

An attachment theory perspective in the examination of relational processes associated with coach-athlete dyads [PDF]

, 2013
The aim of the current study was to examine actor and partner effects of (a) athletes' and coaches' attachment styles (avoidant and anxious) on the quality of the coach-athlete relationship, and (b) athletes' and coaches' quality of the coach-athlete ...
Jowett, Sophia, Lafrenière, Marc-André, Davis, Louise   +2 more
core  

Athletes’ perceived use of information sources when forming initial impressions and expectancies of a coach: An explorative study [PDF]

, 2008
This study aimed to investigate the impact of coach reputation and gender on athletes' expectancies of coaching competency. Male and female athletes (n = 304) viewed a coach profile (i.e., photograph and brief description of the target coach) before ...
Manley, A, Filby, William, Graydon, Jan, Iain Greenlees, Matthew Smith, Greenlees, I., Manley, Andrew J., Smith, MJ, Fllby, WCD, Filby, William C. D., Thelwell, Richard, Smith, Matthew J., Thelwell, R, Richard Thelwell, Graydon, J, Manley, A., Greenlees, Iain A., Manley, AJ, Greenlees, I, Smith, M, Thelwell, Richard C., Greenlees, Iain, Andrew Manley   +22 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Career development of expert coaches [PDF]

, 2009
Careers in coaching are a relatively new phenomenon in the UK and at present appear to be limited to the performance coach. This study, using an interview approach, examined the transition of expert coaches (n = 9) through various stages in their careers.
Nash, Christine; id_orcid, Sproule, John
core   +1 more source