Results 231 to 240 of about 3,171 (281)
Abstract Sinking biogenic particles drive the ocean biological carbon pump (BCP), yet the processes governing their formation, transformation, and fate remain poorly constrained and are difficult to represent with existing modeling frameworks. Traditional approaches either resolve particle populations as bulk distributions or simulate individual ...
A. Rufas, S. Khatiwala, T. Jokulsdottir
wiley +1 more source
First‐in‐human outpatient management of recurrent NMIBC with the Multi4 instrument
Objectives To evaluate the feasibility, safety and diagnostic performance of outpatient management of recurrent non‐muscle‐invasive bladder cancer (NMIBC) under local anaesthesia using the Multi4 instrument, a series of preclinical studies were performed followed by a first‐in‐human clinical investigation.
Miden Melle‐Hannah +4 more
wiley +1 more source
A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu +9 more
wiley +2 more sources
Hypoxia‐Driven CA2 Promotes Trophoblast Dysfunction in Preeclampsia
CA2 is upregulated in preeclampsia and impairs trophoblast function by suppressing VEGFA under hypoxia/HIF‐1α signaling. LNP‐mediated CA2 silencing improves placental structure and fetal outcomes, highlighting CA2 as a promising therapeutic target for PE.
Lujiao Chen +7 more
wiley +1 more source
[Clinical practice guideline on the management of patients with dyspepsia. Update 2012]. [PDF]
Gisbert JP +9 more
europepmc +1 more source
Loss of Acid Ceramidase in Myeloid Cells Protects From Chronic Colitis in IL10‐Deficient Mice
Acid ceramidase converts ceramide to sphingosine which can then be converted to sphingosine‐1‐phosphate, a bioactive lipid involved in inflammation. Loss of acid ceramidase in myeloid cells protects from chronic colitis by reducing pro‐inflammatory markers, increasing ceramides, and reducing effector immune cells in the colon.
Keila S. Espinoza +13 more
wiley +1 more source
This gold nanoparticle–chitosan (AuNP@chitosan) composite promotes burn wound healing by simultaneously regulating endothelial and immune responses. In vitro, the composite protects TNF‐α‐injured HUVECs by reducing ROS, restoring thrombomodulin, and upregulating hypoxia‐adaptive markers.
Sheng‐Der Hsu +6 more
wiley +1 more source

