Results 231 to 240 of about 3,171 (281)

SLAMS‐2.0: A Stochastic, Lagrangian Particle‐Resolving Modeling Framework for Investigating the Biological Carbon Pump

open access: yesJournal of Advances in Modeling Earth Systems, Volume 18, Issue 11, November 2026.
Abstract Sinking biogenic particles drive the ocean biological carbon pump (BCP), yet the processes governing their formation, transformation, and fate remain poorly constrained and are difficult to represent with existing modeling frameworks. Traditional approaches either resolve particle populations as bulk distributions or simulate individual ...
A. Rufas, S. Khatiwala, T. Jokulsdottir
wiley   +1 more source

First‐in‐human outpatient management of recurrent NMIBC with the Multi4 instrument

open access: yesBJU International, Volume 138, Issue 5, Page 867-876, November 2026.
Objectives To evaluate the feasibility, safety and diagnostic performance of outpatient management of recurrent non‐muscle‐invasive bladder cancer (NMIBC) under local anaesthesia using the Multi4 instrument, a series of preclinical studies were performed followed by a first‐in‐human clinical investigation.
Miden Melle‐Hannah   +4 more
wiley   +1 more source

Created Ex Nihilo: A Near‐Infrared Afterglow Luminescent Framework of Imidazole Derivatives for Bioimaging

open access: yesAngewandte Chemie, Volume 138, Issue 43, 19 October 2026.
A series of Ir(III) complexes (Ir‐1‐Ir‐4) based on imidazole derivatives provide a new afterglow luminescence mechanism. The work expands the range of afterglow luminescence frameworks to overcome: (i) a lack of new afterglow scaffolds; (ii) the dependence on initial external light activation; and (iii) aggregation‐caused quenching.
Zihan Wu   +9 more
wiley   +2 more sources

Hypoxia‐Driven CA2 Promotes Trophoblast Dysfunction in Preeclampsia

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
CA2 is upregulated in preeclampsia and impairs trophoblast function by suppressing VEGFA under hypoxia/HIF‐1α signaling. LNP‐mediated CA2 silencing improves placental structure and fetal outcomes, highlighting CA2 as a promising therapeutic target for PE.
Lujiao Chen   +7 more
wiley   +1 more source

[Clinical practice guideline on the management of patients with dyspepsia. Update 2012]. [PDF]

open access: yesAten Primaria, 2012
Gisbert JP   +9 more
europepmc   +1 more source

Loss of Acid Ceramidase in Myeloid Cells Protects From Chronic Colitis in IL10‐Deficient Mice

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Acid ceramidase converts ceramide to sphingosine which can then be converted to sphingosine‐1‐phosphate, a bioactive lipid involved in inflammation. Loss of acid ceramidase in myeloid cells protects from chronic colitis by reducing pro‐inflammatory markers, increasing ceramides, and reducing effector immune cells in the colon.
Keila S. Espinoza   +13 more
wiley   +1 more source

Targeting Oxidative and Immune Dysregulation in Wound Healing via Gold Nanoparticle Conjugate Chitosan

open access: yesThe FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This gold nanoparticle–chitosan (AuNP@chitosan) composite promotes burn wound healing by simultaneously regulating endothelial and immune responses. In vitro, the composite protects TNF‐α‐injured HUVECs by reducing ROS, restoring thrombomodulin, and upregulating hypoxia‐adaptive markers.
Sheng‐Der Hsu   +6 more
wiley   +1 more source

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