Results 1 to 10 of about 637,976 (296)

Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia

Journal of Thrombosis and Haemostasis, 2020
In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.
N. Tang, Dengju Li, Xiong Wang, Ziyong Sun   +3 more
semanticscholar   +2 more sources

Utility of ACMG classification to support interpretation of molecular genetic test results in patients with factor VII deficiency

Frontiers in Medicine, 2023
BackgroundThe American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP) have introduced an internationally shared framework for variant classification in genetic disorders.
Rosa Sonja Alesci, Carola Hecking, Benjamin Racké, Detlev Janssen, Carl-Erik Dempfle   +4 more
doaj   +1 more source

Recombinant factor IX‐Fc fusion protein in severe hemophilia B: Patient‐reported outcomes and health‐related quality of life

Research and Practice in Thrombosis and Haemostasis, 2021
Introduction In 2017, all people with severe hemophilia B in Ireland switched to recombinant factor IX Fc fusion protein concentrate (rFIXFc) prophylaxis.
Mairead O’Donovan, Eimear Quinn, Kate Johnston, Evelyn Singleton, Julie Benson, Brian O'Mahony, Declan Noone, Cleona Duggan, Ruth Gilmore, Kevin Ryan, James S. O'Donnell, Niamh M. O’Connell   +11 more
doaj   +1 more source

Higher cyclosporine-A concentration increases the risk of relapse in AML following allogeneic stem cell transplantation from unrelated donors using anti-thymocyte globulin

Scientific Reports, 2023
Cyclosporine-A (CsA) is used to prevent acute graft-versus-host disease (aGvHD). European Society for Blood and Marrow transplantation (EBMT) recommends a CsA target serum concentration of 200–300 µg/L during the first month after allogeneic ...
Mikael Lisak, Malin Nicklasson, Robert Palmason, Stina Wichert, Cecila Isaksson, Per-Ola Andersson, Jan-Erik Johansson, Stig Lenhoff, Mats Brune, Markus Hansson   +9 more
doaj   +1 more source

Direct Oral Anticoagulant removal by a DOAC filter: Impact on lupus anticoagulant testing – Evaluation on spiked and patient samples

Research and Practice in Thrombosis and Haemostasis, 2022
Background DOAC Filter (DF) is a new device to overcome interference in lupus anticoagulant (LAC) testing by direct oral anticoagulants (DOACs). Objectives We evaluated DOAC removal from plasma and elimination of DOAC interference in LAC testing by DF ...
Eleni A. Linskens, Pieter De Kesel, Katrien M. J. Devreese   +2 more
doaj   +1 more source

Prominent changes in blood coagulation of patients with SARS-CoV-2 infection

Clinical Chemistry and Laboratory Medicine, 2020
Background As the number of patients increases, there is a growing understanding of the form of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has caused an outbreak in China.
Huan Han, Lan Yang, R. Liu, Fang Liu, Kailang Wu, Jie Li, Xinghui Liu, Chengliang Zhu   +7 more
semanticscholar   +1 more source

COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection

Blood, 2020
Patients with coronavirus disease 2019 (COVID-19) have elevated D-dimer levels. Early reports describe high venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC) rates, but data are limited.
Hanny Al‐Samkari, R. K. Karp Leaf, W. Dzik, J. Carlson, Annemarie E. Fogerty, A. Waheed, Katayoon Goodarzi, Pavan K Bendapudi, L. Bornikova, Shruti Gupta, D. Leaf, D. Kuter, R. Rosovsky   +12 more
semanticscholar   +1 more source

Endothelial cells and coagulation

Cell and Tissue Research, 2021
Endothelial cells form a monolayer, which lines blood vessels. They are crucially involved in maintaining blood fluidity and providing controlled vascular hemostasis at sites of injury.
Katharina Neubauer, B. Zieger
semanticscholar   +1 more source

Heparin-induced thrombocytopenia and COVID-19

Hematology Reports, 2021
Heparin-induced thrombocytopenia (HIT) has not been included as a possible cause of thrombocytopenia in Coronavirus Disease 2019 (COVID-19) patients. We report a case of HIT in a patient with COVID-19 treated with heparin.
Michelangelo Sartori, Benilde Cosmi
doaj   +1 more source

Analysis of dynamic disturbance in blood coagulation function of patients with Coronavirus Disease 2019

American Journal of Respiratory and Critical Care Medicine, 2020
Coronavirus Disease 2019 (COVID-19) has became a major problem affecting global health security. To assess the differences and dynamic changes of blood coagulation function in COVID-19 patients with different severity.
Yingzhen Du, L. Tu, Pingjun Zhu, M. Mu, Runsheng Wang, Pengcheng Yang, Xi Wang, Chao Hu, Rongyu Ping, Peng Hu, Tianzhi Li, F. Cao, Christopher Chang, Q. Hu, Yang Jin, Guogang Xu   +15 more
semanticscholar   +1 more source