Results 191 to 200 of about 508,637 (297)

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Can prothrombin time assays withstand the influence of antiprothrombin and anti-β2-glycoprotein I antibodies on the international normalized ratio?

Research and Practice in Thrombosis and Haemostasis
Arne Vandevelde, Katrien M.J. Devreese
doaj   +1 more source

Comparative efficacy of nerve coagulation vs. cap implantation in neuroma prevention using the rat sciatic nerve model: A histological and neuroradiological insight. [PDF]

PLoS One
Aman M, Klemm TT, Mayrhofer-Schmid M, Panayi AC, Brunnée M, Schwarz D, Harhaus L, Boecker AH.   +7 more
europepmc   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

the pharmacological management of genetically determined coagulation disorders

This thesis explores the pharmacological management of inherited blood coagulation disorders, which include both hemorrhagic conditions like hemophilia A and B and von Willebrand disease, as well as thrombophilic disorders such as Factor V Leiden ...
Yokoshima, Kotone
core  

Magnetoelastic Sensors-Based Pumpless Microfluidic Chip for Point-of-Care Coagulation Kinetics Monitoring. [PDF]

Biosensors (Basel)
Lu Y, Liang W, Qian J, Li J, Wu S, Xia M, Sun H.   +6 more
europepmc   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Impact of Whole-Body Cryostimulation (WBC) on Hemostatic Parameters in Patients with Multiple Sclerosis. [PDF]

J Clin Med
Zielińska-Nowak E, Dziedzic A, Lipert A, Kolodziejczyk-Czepas J, Saluk J, Miller E.   +5 more
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Plasma Proteomic Profiling Reveals Alterations in Coagulation, Complement, and Extracellular Matrix Pathways in Orthostatic Hypotension. [PDF]

JACC Adv
Johansson M, Végvári Á, Engström G, Fedorowski A.   +3 more
europepmc   +1 more source