Artificial Organs, EarlyView.In this single‐center retrospective cohort study, the use of PMX‐HA was significantly associated with a reduced risk of 1‐year mortality in patients with septic shock due to intra‐abdominal infection. In contrast, no significant association was observed between PMX‐HA use and 1‐year mortality risk in patients with septic shock caused by extra‐abdominal
Tomoki Tanaka +9 more
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Medical haematology: Repositioning haematology at the centre of medicine
British Journal of Haematology, EarlyView.The complementary domains of Medical Haematology and Haemato‐Oncology share a biological framework. The left panel depicts red cells, platelets, coagulation, thrombosis and innate immunity, while the right panel shows lymphoid and myeloid malignancies.
Cheng Hock Toh, Imelda Bates, Sue Pavord
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Frontiers in PediatricsIntroductionCardiopulmonary bypass (CPB) causes coagulopathy, increasing the risk of postoperative bleeding and mortality. The underlying causes of post-CPB coagulopathy and the factors associated with its occurrence are not yet fully understood.
Margherita Plebani +4 more
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Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, EarlyView.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
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Viscoelastic Testing and Coagulopathy of Traumatic Brain Injury [PDF]
, 2021 Jamie Bradbury +19 more
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Clinical Otolaryngology, EarlyView.ABSTRACT Objective To assess if surgery for Obstructive Sleep Apnea Disorder (OSAD) is safe for infants and toddlers. Methods Retrospective cohort study of paediatric patients undergoing OSA surgery; partial or complete tonsillectomy with adenoidectomy, tonsillectomy without adenoidectomy and adenoidectomy.
Daniel Levi +8 more
wiley +1 more source
Recent Advances in Pathogenesis and Anticoagulation Treatment of Sepsis-Induced Coagulopathy
Journal of Inflammation ResearchChit Man,* Yuan An,* Guo-Xin Wang,* En-Qiang Mao, Li Ma Department of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this ...
Man C, An Y, Wang GX, Mao EQ, Ma L
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Covid-19: Consumption coagulopathy with increased severity and mortality - A retrospective study
, 2022 Kunal Gaur +2 more
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COVID–19-associated coagulopathy: An exploration of mechanisms [PDF]
, 2020 Meaghan Colling, Yogendra Kanthi
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SARS-CoV-2 Spike Proteins and Cell–Cell Communication Induce P-Selectin and Markers of Endothelial Injury, NETosis, and Inflammation in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for the Pathogenesis of COVID-19 Coagulopathy [PDF]
, 2023 Biju Bhargavan, Georgette D. Kanmogne
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