Results 151 to 160 of about 122,436 (294)
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
British Journal of Pharmacology, EarlyView.Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
RNA Analysis Uncovers Pathogenic PARN Variant in Dyskeratosis Congenita
Clinical Genetics, EarlyView.Using WGS and RNA analysis, we identified a branch point‐disrupting variant in the PARN gene and elucidated its pathogenic molecular mechanism in a child with atypical dyskeratosis congenita presentation. ABSTRACT Dyskeratosis congenita (DC) is a rare genetic disorder caused by impaired telomere maintenance, leading to diverse clinical manifestations ...
Daria Akimova +3 more
wiley +1 more source
Neutrophil-to-lymphocyte ratio predicts mortality for sepsis-induced coagulopathy: a retrospective study [PDF]
Hui Zhong +4 more
openalex +1 more source
Clinical Oral Implants Research, EarlyView.ABSTRACT Objectives To compare the clinical and radiographic outcomes of crestal sinus floor elevation (SFE) using a digital surgical guide (DSG) and hydraulic sinus lift technique versus the conventional osteotome technique. Methods Patients requiring crestal SFE and single‐implant placement in the posterior maxilla with a minimum of 5 mm of residual ...
Mahsa Enssi +4 more
wiley +1 more source
Venous thromboembolism related to cytomegalovirus infection: A case report and literature review [PDF]
, 2017 Farrell, John J +3 more
core +2 more sources
Coagulopathy in a patient with X‐linked hyper‐IgM syndrome who developed Kaposi's sarcoma [PDF]
, 2004 Masayuki Nagasawa +5 more
openalex +1 more source
Endothelial dysfunction contributes to COVID-19-associated vascular inflammation and coagulopathy [PDF]
, 2020 Jun Zhang +2 more
openalex +1 more source
Clinical Otolaryngology, EarlyView.ABSTRACT Introduction Sarcopenia and frailty status have been shown to be associated with cancer patients' survival. Low alanine aminotransferase (ALT) blood activity was previously shown to be associated with frailty and poor clinical outcomes in cancer patients. This association was not addressed in head and neck cancer patients.
Yarden Tenenbaum Weiss +8 more
wiley +1 more source