Results 181 to 190 of about 94,409 (286)

Advanced Molecular Analysis in Hemophilia A in a Single Step: Next Generation Sequencing (NGS) and Copy Number Variation (CNV) Analysis

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Hemophilia A, an X‐linked bleeding disorder caused by pathogenic variants in the F8 gene, requires precise genetic diagnosis for optimal management. Conventional stepwise sequence and copy number variation (CNV) analyses are time‐consuming and may leave some cases unresolved.
Enise Avci Durmusalioglu, Esra Isik, Basak Durmus Ozen, Mehmet Mert Topaloglu, Nihal Karadas, Kaan Kavakli, Melike Sezgin Evim, Tolga Aslan, Erşen Kavak, Adalet Meral Gunes, Funda Tayfun Kupesiz, Alphan Kupesiz, Fahri Sahin, Tahir Atik   +13 more
wiley   +1 more source

Role of Thromboelastometry in Sepsis-Induced Coagulopathy: A Narrative Review. [PDF]

Med Sci (Basel)
Lubiewski A, Siemiński M.
europepmc   +1 more source

What do we know about nephrotoxicity of NSAIDs in horses?

Equine Veterinary Education, EarlyView.
C. Di Donato, G. van Galen
wiley   +1 more source

Thrombocytopenia in Pregnancy: A 5‐Year Analysis of Characteristics and Practices From a Tertiary Academic Center

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Moderate‐to‐severe thrombocytopenia (platelet count < 100 × 109/L) occurs in fewer than 1% of pregnancies, posing management challenges, particularly surrounding eligibility for neuraxial anesthesia. Although recent anesthesia guidelines recommend a platelet threshold ≥ 70 × 109/L, outcomes data applying these recommendations in ...
Mackenzie E. Lemieux, Ming Y. Lim
wiley   +1 more source

Glutathione S-Transferase Omega 1 Promotes Macrophage Inflammation-Associated Coagulopathy in Sepsis by S-Glutathionylating ANXA5 to Enhance Its Ubiquitination. [PDF]

FASEB J
Peng J, Hu C, Fu X, Li S, Liu W, Peng J.
europepmc   +1 more source

How I Investigate Bleeding Disorders of Unknown Cause: Current Diagnostic Pathways and Gaps in Laboratory Investigation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Bleeding disorder of unknown cause (BDUC) constitutes the largest group of patients presenting with a mild‐to‐moderate bleeding tendency in tertiary care settings. Their clinical bleeding phenotype is characterized by mucocutaneous bleeding, as well as bleeding following surgical challenges or childbirth, and is associated with impaired health‐
Dino Mehic, Faris Karaselimovic, Tim Dreier, Johanna Gebhart   +3 more
wiley   +1 more source

Sepsis-associated thrombotic microangiopathy-like syndrome following cardiac surgery: a case report. [PDF]

Front Cardiovasc Med
Yang C, Dong S, Xia Z, Peng W, Yan H, Zhang Z, Wei Q.   +6 more
europepmc   +1 more source

Coagulation and Fibrinolysis in Normal Pregnancy and Complicated Pregnancy

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Pregnancy induces significant physiological changes in the hemostatic system, leading to a hypercoagulable state to prevent postpartum hemorrhage. These adaptations involve alterations in coagulation and fibrinolysis, which can be further modified in complicated pregnancies such as gestational diabetes mellitus (GDM) and ...
Yang Su, Yao Wei, Cheng Liu, Yafei Gao, Xiaolong Ma, Yongxin Li, Rui Qiao   +6 more
wiley   +1 more source

Amniotic Fluid Embolism With Maternal and Neonatal Survival in the Setting of Previously Undiagnosed Placenta Accreta Spectrum 3D: A Case Report. [PDF]

Cureus
Schaefer D, Beaty MA, Chalifour S, Braverman JA, Christensen B.   +4 more
europepmc   +1 more source