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Snakebite affects around 2.5 million humans annually, with greater than 100,000 deaths. Coagulopathy is a significant cause of both morbidity and mortality in these patients, either directly, or indirectly.
Julian White
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The problem with coagulopathy …
Journal of Thrombosis and Haemostasis, 2022Coagulopathy is inextricably linked to the field of hemostasis and thrombosis. In the same manner hemostasis and thrombosis may deal with bleeding and clot formation, coagulopathy also may be connected to bleeding or thrombosis, depending on the circumstances.
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Critical Care Nursing Clinics of North America, 1993
Because complications associated with postoperative coagulopathies are significant, prevention, early evaluation, and appropriate management are essential. The etiologies of postoperative coagulopathies are multifactorial and can be evaluated by a systematic clinical approach. Treatment should not be arbitrary but directed at specific defects.
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Because complications associated with postoperative coagulopathies are significant, prevention, early evaluation, and appropriate management are essential. The etiologies of postoperative coagulopathies are multifactorial and can be evaluated by a systematic clinical approach. Treatment should not be arbitrary but directed at specific defects.
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Thrombosis and Haemostasis, 2004
SummaryDisseminated intravascular coagulation (DIC) is a common phenomenon in patients with sepsis, but the clinical implications of this condition are not clear. Clinical trials with coagulation inhibitors have failed to show a significant benefit concerning survival. DIC is primarily a laboratory diagnosis, based on the combination of elevated fibrin-
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SummaryDisseminated intravascular coagulation (DIC) is a common phenomenon in patients with sepsis, but the clinical implications of this condition are not clear. Clinical trials with coagulation inhibitors have failed to show a significant benefit concerning survival. DIC is primarily a laboratory diagnosis, based on the combination of elevated fibrin-
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Current Opinion in Hematology, 2014
To provide an updated overview of the complex coagulopathy associated with malignancy, together with the advances in our knowledge of the interactions of cancer with the hemostatic system. Also, to offer an update of the recent progresses in the risk assessment, prevention, and treatment of thrombohemorrhagic complications in cancer patients.Mechanisms
Falanga, A, Russo, L, Milesi, V
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To provide an updated overview of the complex coagulopathy associated with malignancy, together with the advances in our knowledge of the interactions of cancer with the hemostatic system. Also, to offer an update of the recent progresses in the risk assessment, prevention, and treatment of thrombohemorrhagic complications in cancer patients.Mechanisms
Falanga, A, Russo, L, Milesi, V
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Veterinary Clinics of North America: Equine Practice, 2014
Although primary coagulopathies are rare in horses, changes in coagulation and fibrinolysis are commonly associated with inflammatory diseases. A clear understanding of the pathophysiology of normal and abnormal hemostasis is required to be able to choose and interpret diagnostic tests evaluating coagulation and fibrinolysis. After diagnosis, treatment
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Although primary coagulopathies are rare in horses, changes in coagulation and fibrinolysis are commonly associated with inflammatory diseases. A clear understanding of the pathophysiology of normal and abnormal hemostasis is required to be able to choose and interpret diagnostic tests evaluating coagulation and fibrinolysis. After diagnosis, treatment
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Thrombosis Research, 2014
Blood coagulation activation is frequently found in patients with malaria. Clinically apparent bleeding or disseminated intravascular coagulation (DIC) is associated with very severe disease and a high mortality. Protein C, protein S, and antithrombin levels were found to be low in P. falciparum, but were normal in P. vivax infection.
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Blood coagulation activation is frequently found in patients with malaria. Clinically apparent bleeding or disseminated intravascular coagulation (DIC) is associated with very severe disease and a high mortality. Protein C, protein S, and antithrombin levels were found to be low in P. falciparum, but were normal in P. vivax infection.
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Coagulopathies and Vasculopathies
1992These diseases, manifested by vascular occlusion, hemorrhage, or both, have a variety of causes. For didactic purposes, we are arbitrarily dividing this very heterogeneous group of lesions into three subgroups: (1) coagulopathies, (2) cerebrovascular disorders of cardiovascular origin, and (3) inflammatory and dysmetabolic vasculopathies.
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Veterinary Clinics of North America: Equine Practice, 2008
The most common cause of hemorrhage is vascular injury; however, the possibility of hemostatic failure should be considered in the initial differential diagnosis. This article provides an overview of preliminary screening and definitive tests to identify hemostatic defects in horses.
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The most common cause of hemorrhage is vascular injury; however, the possibility of hemostatic failure should be considered in the initial differential diagnosis. This article provides an overview of preliminary screening and definitive tests to identify hemostatic defects in horses.
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