Results 71 to 80 of about 88,380 (294)

Step‐by‐Step Technique for Platelet‐Rich Plasma Gel Preparation and Use in Knee Osteoarthritis

Arthroscopy Techniques, EarlyView.
Abstract Knee osteoarthritis (OA) remains a leading cause of pain and disability worldwide, and current injectable options such as corticosteroids and hyaluronic acid often provide limited or short‐term benefits. Orthobiologic therapies, particularly platelet‐rich plasma (PRP), have gained attention for their regenerative and anti‐inflammatory ...
Diego Ariel de Lima, Renata Clazzer, Carlos Eduardo da Silveira Franciozi, Ávila Kelly de Medeiros Nicolau, Isadora Pereira Bandeira, Lana Lacerda de Lima, Maria Luzete Costa Cavalcante   +6 more
wiley   +1 more source

COVID-19 Associated Coagulopathy and Implications for its Treatment

Acta Medica Bulgarica, 2020
The SARS-CoV-2 coronavirus (COVID-19) pandemic is due to lack of prior immunity and there is no certain management, regarding the complications of this viral illness. The target organ for COVID-19 infection are the lungs.
Cherneva Zh., Cherneva R.
doaj   +1 more source

COVID-19 Related Coagulopathy: A Distinct Entity?

, 2020
The coronavirus disease 2019 (COVID-19) pandemic has impacted healthcare communities across the globe on an unprecedented scale. Patients have had diverse clinical outcomes, but those developing COVID-19-related coagulopathy have shown a ...
Olivier Morel, Sattler, Laurent, Grunebaum, Lelia, Marchandot, Benjamin, Matsushita, Kensuke, Lelia Grunebaum, Jesel, Laurence, Valerie Schini-Kerth, Schini-Kerth, Valerie, Laurence Jesel, Morel, Olivier, Benjamin Marchandot, Laurent Sattler, Kensuke Matsushita   +13 more
core   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

Disseminated intravascular coagulopathy caused by Kikuchi–Fujimoto disease resulting in death: first case report in Turkey

, 2014
Emine Uslu,1 Sibel Gurbuz,2 Abdulsamet Erden,1 Fatma Aykas,1 Hatice Karagoz,1 Samet Karahan,1 Hatice Karaman,3 Ali Cetinkaya,1 Deniz Avci1 1Internal Medicine Department, 2Infection Disease Department, 3Clinical Pathology Department, Kayseri Training and ...
Karahan S, Cetinkaya A, Karaman H, Gurbuz S, Erden A, Avci D, Aykas F, Uslu E, Karagoz H   +8 more
core  

The use of two novel techniques in the coagulopathic trauma patient in intensive care [PDF]

, 2009
Severe Trauma is a multisystem disorder with a high mortality in an often young population. It offers a big challenge to the intensivist, and any help that is available might prove decisive in saving the patient’s life.
Aquilina, Andrew, Sciberras, Stephen C.
core  

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Complement Overactivation as a Causal Driver of Sepsis-Associated Coagulopathy: A Mendelian Randomization Study from the UK Biobank

Clinical and Applied Thrombosis/Hemostasis
Background This study aimed to investigate the causal relationship between complement system overactivation and coagulopathy in sepsis using a two-sample Mendelian Randomization (MR) approach.
Rong Liufu MD, Mao-Mao Cao MD, Yan Chen MD, Yang-Yan-Qiu Wang MD, Yao Wu MD, Wei Jiang MD, Jin-Min Peng MD, Bin Du MD, Li Weng MD   +8 more
doaj   +1 more source

A prospective series of acute rivaroxaban overdose, coagulopathy and bleeding complications (ATOM 11)

British Journal of Clinical Pharmacology, EarlyView.
Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi, Angela L. Chiew, Keith Harris, Geoffrey K. Isbister   +3 more
wiley   +1 more source