Results 61 to 70 of about 21,153 (309)

Enabling community input to improve equity in and access to translational research: The Community Coalition for Equity in Research

Journal of Clinical and Translational Science, 2022
Background: The COVID vaccine trials illustrated the critical need for the development of mechanisms to serve as a bridge between least advantaged communities and researchers.
Karen M. Emmons, Michael Curry, Rebekka M. Lee, Albert Pless, Shoba Ramanadhan, Carolina Trujillo   +5 more
doaj   +1 more source

Learning Coalition Structures with Games

Proceedings of the AAAI Conference on Artificial Intelligence
Coalitions naturally exist in many real-world systems involving multiple decision makers such as ridesharing, security, and online ad auctions, but the coalition structure among the agents is often unknown. We propose and study an important yet previously overseen problem -- Coalition Structure Learning (CSL), where we aim to carefully design a series ...
Yixuan Even Xu, Chun Kai Ling, Fei Fang 0001   +2 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Gamson–Shapley Laws: a formal approach to parliamentary coalition formation

Humanities & Social Sciences Communications, 2023
We consider a set of empirical assumptions formulated by Gamson (1961), namely, Gamson’s Laws, which remain at the heart of government formation forecast in parliamentary systems.
Nataliya Demyanenko, Pierfrancesco La Mura   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Balanced Weights and Three-Sided Coalition Formation

Games, 2010
We consider three-sided coalition formation problems when each agent is concerned about his local status as measured by his relative rank position within the group of his own type and about his global status as measured by the weighted sum of the average
Emiliya Lazarova, Dinko Dimitrov
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Anytime coalition structure generation in multi-agent systems with positive or negative externalities

, 2012
In contrast, very little attention has been given to the more general class of Partition Function Games, where the emphasis is on how the formation of one coalition could influence the performance of other co-existing coalitions in the system.
Michalak, T, Nicholas R. Jennings, Rahwan, Talal, Jennings, Nicholas R., Talal Rahwan, Michalak, Tomasz, Michael Wooldridge, Rahwan, T, Jennings, NR, Wooldridge, Michael, Wooldridge, M, Tomasz Michalak   +11 more
core   +1 more source

The problem of generation in a foster family as a special small social group

Социальная психология и общество, 2019
The peculiarities of changes in the structure of a foster family after the child adoption, related to the restructuring of borders, rules, norms that exist in the family before adoption are discussed.
Makhnach A.V.
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source