Results 71 to 80 of about 367,456 (306)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The problem of generation in a foster family as a special small social group
The peculiarities of changes in the structure of a foster family after the child adoption, related to the restructuring of borders, rules, norms that exist in the family before adoption are discussed.
Makhnach A.V.
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Graph Coalition Structure Generation
We give the first analysis of the computational complexity of {\it coalition structure generation over graphs}. Given an undirected graph $G=(N,E)$ and a valuation function $v:2^N\rightarrow\RR$ over the subsets of nodes, the problem is to find a partition of $N$ into connected subsets, that maximises the sum of the components' values.
Voice, Thomas D. +2 more
openaire +2 more sources
Rationing rules and stable coalition structures
We consider a coalition formation model in which agents have the possibility of forming part of several coalitions but are limited to participate in only one of them. Coalitions of agents produce outputs to be distributed among their members according to their aspirations and to a rationing rule prevailing in society. The outcome of such a process is a
Gallo Fernández, Oihane +1 more
openaire +5 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Contractually Stable Networks [PDF]
We develop a theoretical framework that allows us to study which bilateral links and coalition structures are going to emerge at equilibrium. We define the notion of coalitional network to represent a network and a coalition structure, where the network ...
Ana Mauleon +2 more
core +9 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Coalition Formation among Farsighted Agents [PDF]
A set of coalition structures P is farsightedly stable (i) if all possible deviations from any coalition structure p belonging to P to a coalition structure outside P are deterred by the threat of ending worse off or equally well off, (ii) if there ...
Herings P. Jean-Jacques +2 more
core +1 more source

