Results 31 to 40 of about 5,615 (251)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Sequentially optimal repeated coalition formation under uncertainty [PDF]
Coalition formation is a central problem in multiagent systems research, but most models assume common knowledge of agent types. In practice, however, agents are often unsure of the types or capabilities of their potential partners, but gain information ...
Chalkiadakis, Georgios +3 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The wind–solar–storage–thermal combined power generation system is one of the key measures for China’s energy structure transition, and rational capacity planning of each generation entity within the system is of critical importance.
Zhiding Chen +3 more
doaj +1 more source
Graph Coalition Structure Generation
We give the first analysis of the computational complexity of {\it coalition structure generation over graphs}. Given an undirected graph $G=(N,E)$ and a valuation function $v:2^N\rightarrow\RR$ over the subsets of nodes, the problem is to find a partition of $N$ into connected subsets, that maximises the sum of the components' values.
Thomas Voice +2 more
openaire +2 more sources
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
In contrast, very little attention has been given to the more general class of Partition Function Games, where the emphasis is on how the formation of one coalition could influence the performance of other co-existing coalitions in the system.
Michalak, T +11 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source

