Results 41 to 50 of about 189,811 (255)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Solving the Coalition Structure Generation Problem on a GPU [PDF]
, 2016 We develop the first parallel algorithm for Coalition Structure Generation (CSG), which is central to many multi-agent systems applications. Our approach involves distributing the key steps of a dynamic programming approach to CSG across ...
Cerquides, Jesús +4 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Decentralised Coordination in RoboCup Rescue [PDF]
, 2010 Emergency responders are faced with a number of significant challenges when managing major disasters. First, the number of rescue tasks posed is usually larger than the number of responders (or agents) and the resources available to them.
Farinelli, Alessandro +4 more
core +1 more source
An Anytime Algorithm for Optimal Coalition Structure Generation
Journal of Artificial Intelligence Research, 2009 Coalition formation is a fundamental type of interaction that involves the creation of coherent groupings of distinct, autonomous, agents in order to efficiently achieve their individual or collective goals. Forming effective coalitions is a major research challenge in the field of multi-agent systems.
Rahwan, T +3 more
openaire +6 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Salafist movement and sheikh-ism in the Tunisian democratic transition [PDF]
, 2013 The article examines the complexity of Tunisian Salafism in the context of the Tunisian transition to democracy. Building on primary sources and original field work, the article highlights the theoretical and practical divergences that affect the ...
Cavatorta, Francesco, Merone, Fabio
core +2 more sources
The Proceedings of the 2nd International Conference on Industrial Application Engineering 2015, 2015 Forming effective coalitions is a major problem in multiagent systems. Coalition structure generation (CSG) involves partitioning a set of agents into teams, i.e. coalitions. The set of coalitions is a coalition structure. In the context of the CSG research, our goal is forming the coalition structure that maximizes the social surplus.
Katsuya Nakano +3 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source