Results 121 to 130 of about 269,399 (299)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

An equilibrium model with mixed federal structures

Известия Иркутского государственного университета: Серия "Математика", 2014
This paper examines the problem of meeting an inelastic demand for public goods of club type in an economy with a finite number of agents, who exhibit different preferences regarding the choice of public projects.
S. Weber, V.L. Makarov, A.V. Savvateev
doaj  

Internal Hierarchy and Stable Coalition Structures [PDF]

When an agent decides whether to join a coalition or not, she must consider both i) the expected strength of the coalition and ii) her position in the vertical structure within the coalition. We establish that there exists a positive relationship between
In-Uck Park, Massimo Morelli
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Rise and Fall of Tigray People’s Liberation Front (TPLF): Postcolonial Rethinking of Ethnic and Language-Based Federalism in Africa

African Journal of Political Science
The Tigray People’s Liberation Front (TPLF) emerged as an ethno-nationalist political movement on February 18, 1975, initiating an armed struggle primarily based in Dedebit, North-western Tigray.
Seife T.K
doaj   +1 more source

Competitive Outcomes and Endogenous Coalition Formation in an n-Person Game [PDF]

In this paper we study competitive outcomes and endogenous coalition formation in a cooperative n-person transferable utility (TU) game from the viewpoint of general equilibrium theory.For any given game, we construct a competitive exchange coalition ...
Sun, N., Trockel, W., Yang, Z.F.
core   +1 more source

Coalition Structure Generation on Graphs

, 2014
Two fundamental algorithm-design paradigms are Tree Search and Dynamic Programming. The techniques used therein have been shown to complement one another when solving the complete set partitioning problem, also known as the coalition structure generation problem [5].
Rahwan, Talal, Michalak, Tomasz P.
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Coalition structure generation problems

, 2017
The coalition structure generation problem is well known in the area of multi-agent systems. Its goal is to establish coalitions between agents while maximizing the global welfare. Among the existing different algorithms designed to solve the coalition structure generation problem, DP and IDP are the ones with smaller temporal complexity.
Cruz Mencía, Francisco, Cerquides Bueno, Jesus, Rodríguez-Aguilar, Juan A., Espinosa, Antonio, Moure, Juan C, Ramchurn, Sarvapali D., Svensson, Kim   +6 more
openaire   +1 more source

Learning Coalition Structures with Games

Proceedings of the AAAI Conference on Artificial Intelligence
Coalitions naturally exist in many real-world systems involving multiple decision makers such as ridesharing, security, and online ad auctions, but the coalition structure among the agents is often unknown. We propose and study an important yet previously overseen problem -- Coalition Structure Learning (CSL), where we aim to carefully design a series ...
Xu, Yixuan Even, Ling, Chun Kai, Fang, Fei   +2 more
openaire   +2 more sources