Results 131 to 140 of about 14,108 (307)
MathematicsThis paper presents a theoretically grounded integration of deterministic Q-learning with relational game theory (QLRG) for efficiently identifying minimal winning coalitions in Online Social Networks (OSNs).
Duc Nghia Vu, Janos Demetrovics
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Coalition Structure Generation in Multi-Agent Systems With Positive and Negative Externalities
, 2009 Coalition structure generation has received considerable attention in recent research. Several algorithms have been proposed to solve this problem in Characteristic Function Games (CFGs), where every coalition is assumed to perform equally well in any ...
Michalak, T +9 more
core
Building Coalitions: Structure
EDIS, 2015 This document is FY504, Part 12 of the 16 part series adapted for use in Florida by Elizabeth B. Bolton and Lisa Guion.
Elizabeth B. Bolton +2 more
openaire +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A hybrid algorithm for coalition structure generation
, 2012 The current state-of-the-art algorithm for optimal coalition structure generation is IDP-IP—an algorithm that combines IDP (a dynamic programming algorithm due to Rahwan and Jennings, 2008b) with IP (a tree-search algorithm due to Rahwan et al., 2009 ...
Nicholas R. Jennings +5 more
core
Italian Political Science, 2018 According to several scholars, the politicization of issues connected to immigration and the European Union (EU) has generated a new cleavage that now structures political competition in Western Europe.
Stella Gianfreda, Benedetta Carlotti
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Coalition Formation in a Global Warming Game: How the Design of Protocols Affects the Success of Environmental Treaty-Making [PDF]
We combine the newest concepts of non-cooperative coalition theory with a computable general equilibrium model close to the seminal RICE-model of Nordhaus and Yang (1996) to determine stable coalition structures in a global warming game.
Johan Eyckmans, Michael Finus
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source