Results 91 to 100 of about 2,215 (200)

Coats disease: An overview of classification, management and outcomes

open access: yesIndian Journal of Ophthalmology, 2019
Coats disease is an idiopathic retinal vascular disorder with retinal telangiectasia with intraretinal and/or subretinal exudation without appreciable retinal or vitreal traction.
Mrittika Sen   +3 more
doaj   +1 more source

Coats disease in Saudi Arabia

open access: yes, 2019
Purpose: : to study the features and treatment outcomes of Coats disease in Saudi Arabia Methods: : retrospective chart review of patients with Coats disease registered at the King Khaled Eye Specialist Hospital from 1983-2010 Results: : Twenty out
Alqahtani, Abdullah A., Ghazi, Nicola G.
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Coats' disease and Fuchs' heterochromic cyclitis

open access: yes, 1994
The authors present an interesting case of a young boy with unilateral Coats' disease who after ten years of follow-up developed Fuchs' heterochromic cyclitis in the same ...
Kritzinger, E E   +2 more
core   +1 more source

Bilateral Coats’ Disease Combined with Retinopathy of Prematurity [PDF]

open access: yes, 2015
Purpose. To report a case of bilateral Coats’ disease combined with retinopathy of prematurity (ROP). Case. Retinal vascularization was complete in the right eye, whereas zone III, stage 3 ROP and preplus disease were observed in the left eye at 43 weeks
Huseyin Aslan   +5 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Modified transscleral external drainage of subretinal fluid in high bullous exudative retinal detachment due to Coats' disease

open access: yesOman Journal of Ophthalmology, 2018
Surgical management of advanced coats' disease has always been a challenge to a surgeon. Various different techniques have been tried. With the advancement in surgical instruments and machines, surgeons are now modifying older surgical techniques.
Shachi Rohan Desai   +3 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Coats' disease diagnosed in adults: A rare case report

open access: yesTNOA Journal of Ophthalmic Science and Research, 2017
Coats' disease is a form of exudative retinal vasculopathy, commonly diagnosed in the first to second decades. In adults, it usually exhibits a benign course.
Mohan Sivakami   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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