Results 81 to 90 of about 2,215 (200)

Selective Photocoagulation in Coats' Disease: Ten-year Follow-up

open access: yes, 2002
Purpose The diagnostic hallmark of Coats' disease is development of “light bulb” telangiectasis in the retinal periphery, leading to posterior pole intraretinal and subretinal exudation.
M. Serafino   +3 more
core   +2 more sources

Reemergence of dormant Coats disease after 30 years.

open access: yes, 2012
Purpose. We describe an atypical case of a patient with Coats disease that re-emerged after 30 years, illustrating a previously poorly understood long-term evolution of the disease. Methods.
Pérez-Campagne, E., Wolfensberger, T.J.
core   +2 more sources

Subretinal Fluid Drainage and Vitrectomy Are Helpful in Diagnosing and Treating Eyes with Advanced Coats' Disease

open access: yesCase Reports in Ophthalmology, 2016
Severe forms of Coats’ disease are often associated with total retinal detachment, and a differential diagnosis from retinoblastoma is critically important. In such eyes, laser- and/or cryoablation is often ineffective or sometimes impossible to perform.
Ayako Imaizumi   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Coats' disease and calcification: a case report.

open access: yes, 1996
Intraocular calcification can rarely occur in Coats' disease. To our best knowledge, all previously reported cases with intraocular calcification had significant exudative detachment.
Memisoglu, B.   +4 more
core  

Bilateral Fluorescein Angiographic Findings in Unilateral Coats’ Disease

open access: yes, 2011
Two patients with clinically unilateral Coats' disease were imaged with fluorescein angiography during an examination under anesthesia. Both patients were found to have abnormal retinal vasculature in their contralateral eye. These findings may represent
Ditte J. Hess   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Optical Coherence Tomography and Optical Coherence Tomography Angiography in Monitoring Coats’ Disease

open access: yesJournal of Ophthalmology, 2017
Purpose. The aim of this study was to evaluate the usefulness of optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in monitoring pediatric patients with Coats’ disease. Material and Methods.
Wojciech Hautz   +2 more
doaj   +1 more source

Refractory Coats’ Disease of Adult Onset

open access: yesCase Reports in Ophthalmology, 2012
Purpose: We present the case of an 18-year-old Caucasian male with a unilateral macular star and retinal vascular anomalies compatible with adult onset Coats’ disease.
D. Beselga   +5 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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