Results 121 to 130 of about 26,570 (248)

Methionine Synthase Interacts With the Methionine Adenosyl‐Transferase MATα2 and the DNA Methyltransferase DNMT3b in the Nucleus

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
This study shows that methionine synthase (MS) interacts with MATα2, responsible for SAM production, and the methyltransferase DNMT3b in the nucleus. These results support the idea that spatial compartmentalization of one‐carbon metabolism could play a major role in regulating the epigenome.
Manon Jeandel   +8 more
wiley   +1 more source

Homocysteine, Cobalamin and Folate Status and their Relations to Neurocognitive and Psychological Markers in Elderly in Northeastern of Iran [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2013
Objective(s): Incidence of neurocognitive and psychological disorders may be related to serum homocystein (Hcy), cobalamin (vitamin B12 ) and folate levels in old people. The aim of this study was to assess the relation between Hcy, cobalamin, folate and
Lida Manavifar   +6 more
doaj  

Metformin Lowers Serum Cobalamin without Changing Other Markers of Cobalamin Status: A Study on Women with Polycystic Ovary Syndrome

open access: yes, 2013
Treatment with the anti-diabetic drug metformin is followed by a decline in plasma cobalamin, but it is unsettled whether this denotes an impaired cobalamin status.
Ebba Nexo   +4 more
core   +1 more source

Effects of Norbixin on Growth Performance, Immunomodulation, Antioxidant Systems, and Metabolic Alterations in the Oriental River Prawn (Macrobrachium nipponense): An Integrative Analysis

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Dietary norbixin (0.15 g/kg) optimally promotes growth, immunocompetence, antioxidant defence, gut microbial balance, carotenoid accumulation, and overall nutritional quality in Macrobrachium nipponense. ABSTRACT Background Natural carotenoids have gained considerable attention in aquaculture due to their potential to enhance growth performance ...
Mohammad Ettefaghdoost   +2 more
wiley   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 23, 1 June 2026.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl   +1 more
wiley   +1 more source

Behavioral alterations are associated with vitamin B12 deficiency in the transcobalamin receptor/CD320 KO mouse.

open access: yesPLoS ONE, 2017
Vitamin B12 (cobalamin) deficiency is prevalent worldwide and causes megaloblastic anemia and neurologic deficits. While the anemia can be treated, the neurologic deficits can become refractive to treatment as the disease progresses.
Kaveri Arora   +4 more
doaj   +1 more source

Mitochondrial cobalamin binding proteins in patients with inborn errors of cobalamin metabolism

open access: yes, 2006
Vitamin B12 (cobalamin, Cbl) is required as a cofactor for two human enzymes: methylmalonyl-CoA mutase (MCM) and methionine synthase (MS). Fibroblasts from patients with inborn errors of cobalamin metabolism have been classified into nine distinct ...
Moras, Emily.
core  

Ligand Binding Characteristics of the Cobalamin Binder from Zebrafish.

open access: yes, 2012
The zebrafish cobalamin binder (as well as human TC, HC, and IF) was incubated for 18 hours with 57[Co]-cobalamin and increasing concentrations of the unlabeled ligand: cyano-cobalamin (A), dicyano-cobinamide (B) and adenosyl-pseudo-cobalamin (C ...
Eva Greibe (171188)   +2 more
core   +1 more source

Stimuli‐Responsive Crosslinked Chitosan/PVP/PEG Hydrogel Networks for Targeted Drug Delivery and Antimicrobial Performance

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT In this study, a unique pH‐sensitive PEG/C/PVA hydrogel based on chitosan (C), polyvinyl propylene (PVP) and polyethylenglycol (PEG) crosslinked with tetraethyl orthosilicate (TEOS) was fabricated. This PEG/C/PVA hydrogel was designed to deliver different drugs with distinct release profiles, including diclofenac sodium and ciprofloxacin, and ...
Danial Mazhar   +4 more
wiley   +1 more source

Expression of the cobalamin transporters cubam and MRP1 in the canine ileum-Upregulation in chronic inflammatory enteropathy.

open access: yesPLoS ONE
Chronic inflammatory enteropathy (CIE) in dogs, a spontaneous model of human inflammatory bowel disease (IBD), is associated with a high rate of cobalamin deficiency.
Stefanie Kather   +8 more
doaj   +1 more source

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