Results 61 to 70 of about 51,500 (320)

A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans

open access: yesFEBS Open Bio, 2014
In this study, we showed that cyanocobalamin dodecylamine, a ribose 5′-carbamate derivative of cyanocobalamin, was absorbed and accumulated to significant levels by Caenorhabditis elegans and was not further metabolized.
Tomohiro Bito   +4 more
doaj   +1 more source

Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo

open access: yesNature Communications, 2023
Cobalamin-dependent methionine synthase (MS) is a key enzyme in methionine and folate one-carbon metabolism. MS is a large multi-domain protein capable of binding and activating three substrates: homocysteine, folate, and S-adenosylmethionine for ...
Johnny Mendoza   +3 more
doaj   +1 more source

Traceless Regulation of Genetic Circuitry

open access: yesAdvanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? [PDF]

open access: yes, 2016
Background: Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis.
Bosch, Guido   +13 more
core   +2 more sources

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

open access: yesAnimal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem   +5 more
wiley   +1 more source

Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins. [PDF]

open access: yes, 2018
Human gut Bacteroides use surface-exposed lipoproteins to bind and metabolize complex polysaccharides. Although vitamins and other nutrients are also essential for commensal fitness, much less is known about how commensal bacteria compete with each other
Barry, Natasha A   +5 more
core  

Effective pretreatment of wet microalgal biomass to enhance lipid extraction in biodiesel production

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biodiesel is a viable alternative to fossil fuels. Identifying and evaluating nonedible sources is essential to address ecological concerns and meet energy demands. Microalgae are effective for lipid production but their rigid cell walls hinder bioproduct release making the process energy‐intensive and costly.
Amarnath Krishnamoorthy   +2 more
wiley   +1 more source

The relationship between exacerbated diabetic peripheral neuropathy and metformin treatment in type 2 diabetes mellitus

open access: yesScientific Reports, 2021
Metformin-treated diabetics (MTD) showed a decrease in cobalamin, a rise in homocysteine, and methylmalonic acid, leading to accentuated diabetic peripheral neuropathy (DPN). This study aimed to determine whether or not metformin is a risk factor for DPN.
Manal Mohammed Hashem   +3 more
doaj   +1 more source

Methanogenesis marker protein 10 (Mmp10) from Methanosarcina acetivorans is a radical S-adenosylmethionine methylase that unexpectedly requires cobalamin

open access: yesJournal of Biological Chemistry, 2019
Methyl coenzyme M reductase (MCR) catalyzes the last step in the biological production of methane by methanogenic archaea, as well as the first step in the anaerobic oxidation of methane to methanol by methanotrophic archaea.
M. Radle   +3 more
semanticscholar   +1 more source

Adaptive Algal Cultivation Enabled by a Monthly Biomass Forecasting System

open access: yesBiotechnology and Bioengineering, EarlyView.
The developed monthly algal forecasting system used to predict biomass production for two algal strains (A and B) at two pond water depths (low and high). The highest predicted production, achieved with strain A at a low pond water depth, is selected as the cultivation strategy to guide the next month's algal growth.
Hongxiang Yan   +5 more
wiley   +1 more source

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