Results 71 to 80 of about 51,500 (320)

Creatinine, diet, micronutrients, and arsenic methylation in West Bengal, India. [PDF]

, 2011
BackgroundIngested inorganic arsenic (InAs) is methylated to monomethylated (MMA) and dimethylated metabolites (DMA). Methylation may have an important role in arsenic toxicity, because the monomethylated trivalent metabolite [MMA(III)] is highly toxic ...
Basu, Arin, Chung, Joyce, Ghosh, Nilima, Guha Mazumder, DN, Kalman, David, Liaw, Jane, Mitra, Soma, Smith, Allan H, Steinmaus, Craig, von Ehrenstein, Ondine S   +9 more
core   +2 more sources

Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin

Journal of Biological Chemistry, 2017
Riboswitches are a widely distributed class of regulatory RNAs in bacteria that modulate gene expression via small-molecule-induced conformational changes.
J. Polaski, Samantha M. Webster, J. E. Johnson, R. Batey   +3 more
semanticscholar   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

Chemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova, Jieyu Zhao, Chun Kit Kwok   +2 more
wiley   +1 more source

Receptor uptake arrays for vitamin B12, siderophores and glycans shape bacterial communities

, 2017
Molecular variants of vitamin B12, siderophores and glycans occur. To take up variant forms, bacteria may express an array of receptors. The gut microbe Bacteroides thetaiotaomicron has three different receptors to take up variants of vitamin B12 and 88 ...
Frank, Steven A.
core   +1 more source

Elevated Levels of Methylmalonate and Homocysteine in Parkinson's Disease, Progressive Supranuclear Palsy and Amyotrophic Lateral Sclerosis [PDF]

, 2010
Background/Aims: Increasing evidence suggests that elevated levels of homocysteine (Hcy) and methylmalonate (MMA) may be involved in the pathogenesis of neurodegenerative diseases. Methods: The urine levels of MMA and serum levels of Hcy as well as folic
Bötzel, Kai, Giese, Armin, Levin, Johannes, Lorenzl, Stefan, Vogeser, Michael   +4 more
core   +1 more source

Evaluating Red Patches and Burning Mouth Symptoms as Oral Biomarkers in Cobalamin Deficiency: A Comparative Study

Plasmatology
Background Vitamin B12 (cobalamin) deficiency can manifest through various nonspecific oral symptoms. Early diagnosis is crucial but challenging due to subtle and progressive clinical features.
Sanjay Chikkarasinakere Jogigowda MDS, Karthikeya Patil MDS, Varusha Sharon Christopher MDS, Namrata Suresh MDS, Shilpa Padar Shastry MDS, Vidya Gowdappa Doddawad MDS   +5 more
doaj   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

14C-Cobalamin Absorption from Endogenously Labeled Chicken Eggs Assessed in Humans Using Accelerator Mass Spectrometry. [PDF]

, 2019
Traditionally, the bioavailability of vitamin B-12 (B12) from in vivo labeled foods was determined by labeling the vitamin with radiocobalt (57Co, 58Co or 60Co).
Allen, Lindsay H, Buchholz, Bruce A, Calvert, Christopher C, Garrod, Marjorie G, Green, Ralph, Miller, Joshua W, Rossow, Heidi A   +6 more
core   +2 more sources

Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR

Nucleic Acids Research, 2018
The molecular mechanisms that underlie the neurological manifestations of patients with inherited diseases of vitamin B12 (cobalamin) metabolism remain to date obscure.
S. Battaglia-Hsu, Rose Ghemrawi, David Coelho, Natacha Dreumont, Pauline Mosca, Sébastien Hergalant, G. Gauchotte, J. M. Sequeira, Mariam Ndiongue, R. Houlgatte, J. Alberto, Rémy Umoret, Aurélie Robert, J. Paoli, M. Jung, E. Quadros, J. Guéant   +16 more
semanticscholar   +1 more source

Vitamin B12 deficiency in a pediatric patient with gastric obstruction and jejunal feeding dependence: A case report

JPGN Reports, EarlyView.
Abstract Pediatric B12 deficiency is most caused by insufficient dietary intake, malabsorption or autoimmune gastritis. We present a unique case of B12 deficiency in a pediatric patient with complex gastrointestinal anatomy and jejunal nutritional dependence nearly two decades after unsuccessful surgical intervention.
Angela H. Nguyen, Dorsey Bass, Rachel E. Herdes   +2 more
wiley   +1 more source