Results 91 to 100 of about 19,626,692 (182)

Reappraising newborn screening for cobalamin C disorder [PDF]

Pediatrics & Neonatology, 2018
Vlad, Tocan, Kazuhiro, Ohkubo, Kanako, Higashi, Naoko, Toda, Kanako, Kojima-Ishii, Kei, Nishiyama, Masataka, Ishimura, Hidetoshi, Takada, Osamu, Sakamoto, Fusako, Sasaki, Kazuko, Yoshimura, Shinichi, Hirose, Shouichi, Ohga   +12 more
openaire   +2 more sources

Structure of the cobalamin-binding protein of a putative O-demethylase from Desulfitobacterium hafniense DCB-2 [PDF]

, 2013
This study describes the identification and the structural and spectroscopic analysis of a cobalamin-binding protein (termed CobDH) implicated in O-demethylation by the organohalide-respiring bacterium Desulfitobacterium hafniense DCB-2.
Sjuts, Hanno, Dunstan, Mark S, Leys, David, Fisher, Karl   +3 more
core   +1 more source

Successful use of insect‐based (Hermetia illucens) diet in dogs with food‐responsive enteropathy

Journal of Small Animal Practice, EarlyView.
Objective Diet is an integral component of the management of chronic enteropathy in dogs. The role of insect‐based diets in this disease remains unknown. The objective of this study was to evaluate the impact of an insect‐based (Hermetia illucens) diet in dogs with presumed food‐responsive enteropathy.
K. Murtagh, E. Stavroulaki, M. Carvalho, E. J. O'Neill, C. T. Mooney   +4 more
wiley   +1 more source

Cobalamin-Independent Methionine Synthase from Escherichia coli:  A Zinc Metalloenzyme^†

, 2016
Cobalamin-independent methionine synthase (MetE) from Escherichia coli catalyzes the transfer of a methyl group from methyltetrahydrofolate to homocysteine.
James E. Penner-Hahn (1518652), Julio C. González (2948796), Katrina Peariso (795252), Rowena G. Matthews (2379991)   +3 more
core   +1 more source

Retrospective evaluation of outcomes in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban as a sole or adjunctive thromboprophylaxis agent: 34 cases (2018‐2024)

Journal of Small Animal Practice, EarlyView.
Objectives To describe clinical outcomes, thromboembolic and haemorrhagic complications, and treatment characteristics in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban at a UK referral hospital. Materials and Methods Retrospective descriptive study of dogs diagnosed with non‐associative immune‐mediated haemolytic
S. Conway, L. Jenkins, J. Reeve
wiley   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi, Dinh T. Nguyen, Lingyang Zhu, Lide Cha, Jesse W. Wald, Douglas A. Mitchell, Wilfred A. van der Donk   +6 more
wiley   +2 more sources

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

The regulatory roles of liver and kidney in cobalamin (vitamin-B(12)) metabolism in the rat: the uptake and intracellular binding of cobalamin and the activity of the cobalamin-dependent enzymes in response to varying cobalamin supply

, 1984
To examine possible regulatory roles of liver and kidney in cobalamin metabolism, specific activities of the two cobalamin-dependent enzymes, uptake in vivo of cyano [57Co]cobalamin [( 57Co]CNCbl) and the binding of [57Co]Cbl to intracellular proteins ...
Treston, A.M., Cooksley, W.G.E., Bowman, E.P.W., Owens, J.A., Scott, J.S.D.   +4 more
core   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Cobalamin influences pathogenesis at distinct body sites.

, 2019
Each box shows the pathogens demonstrated to rely on cobalamin-dependent processes to grow and/or regulate virulence during infection. (A) Enterococcus faecalis, Salmonella serovar Typhimurium, and Clostridium difficile are shown in the colon.
Carol A. Rowley (6172088), Melissa M. Kendall (753520)   +1 more
core   +1 more source