Results 111 to 120 of about 19,626,692 (182)
Severe pancytopenia at the presentation of Imerslund-Gräsbeck syndrome in a 23-month-old Italian boy
Italian Journal of PediatricsBackground Imerslund-Gräsbeck syndrome (IGS) is a rare autosomal recessive disorder characterized by megaloblastic anemia due to selective cobalamin malabsorption and benign proteinuria.
Francesca Di Sario +7 more
doaj +1 more source
Cyanide Detoxification by the Cobalamin Precursor Cobinamide
, 2006 Cyanide is a highly toxic agent that inhibits mitochondrial cytochrome-c oxidase, thereby depleting cellular ATP. it contributes to smoke inhalation deaths in fires and could be used as a weapon of mass destruction. Cobalamin (vitamin B12) binds cyanide
Immo E. Scheffler +6 more
core +1 more source
Absorbance Spectra of Cobalamin bound to Purified Zebrafish Cobalamin Binder.
, 2012 Spectral characteristics of the zebrafish cobalamin binder in complex with hydroxo-cobalamin are shown. Spectral transition after addition of 15 mM histidine was recorded after 1, 3, 5, 12, 20, and 30 minutes of incubation at room temperature. The arrows
Eva Greibe (171188) +2 more
core +1 more source
Cobalamin C defect: a patient of late-onset type with homozygous p.R132* mutation
The Turkish Journal of Pediatrics, 2013 Methylmalonic aciduria and homocystinuria, cobalamin C (cblC) type, is the most frequent inborn error of vitamin B12metabolism. The clinical phenotype includes systemic symptoms and neurological decompensation.
Mustafa Kılıç +7 more
doaj
BMC PediatricsBackground Cobalamin C (cblC) defect, also referred to as combined methylmalonic acidemia and homocystinuria, is the most common inborn error of intracellular cobalamin metabolism.
Qingmei Huang +4 more
doaj +1 more source
Secretion of Zebrafish Cobalamin-binding Protein to the Ambient Water.
, 2012 Five zebrafish were kept in 100 ml tapped water for six hours and content of cobalamin (A) and unsaturated cobalamin binding capacity (B) in the zebrafish ambient water was measured and compared to the values found in zebrafish protein extracts. Mean and
Eva Greibe (171188) +2 more
core +1 more source
Neuropsychiatric Disease and Treatment, 2019 Sheng-jun Wang, Chuan-zhu Yan, Bing Wen, Yu-ying Zhao Department of Neurology, Qilu Hospital, Shandong University, Jinan, China Objective: The Cobalamin C (cblC) disease is an inborn error of cobalamin metabolism.
Wang S, Yan C, Wen B, Zhao Y
doaj
Synthesis of Cobalamin Analogues Using Enzymatic and Chemical Modification Methods, and Subsequent Identification of Cobalamin Localisation in a Variety of Organisms [PDF]
, 2017 Cobalamin, also known as vitamin B12, is an essential nutrient for many different organisms including mammals, fish, birds, nematodes, and a variety of bacteria. However, cobalamin is only synthesised by a few bacteria and archaea.
Nemoto-Smith, Emi H
core
Molecular Genetics and Metabolism ReportsIntroductionCobalamin c deficiency (cblC), an inborn error of vitamin B12 metabolism, is caused by mutations of the MMACHC gene. It usually leads to a multisystemic disease; 50% of all patients with cblC have various structural heart defects.
Clara Hjalmarsson +7 more
doaj +1 more source
A single rainbow trout cobalamin-binding protein stands in for three human binders
, 2012 Cobalamin uptake and transport in mammals are mediated by three cobalamin-binding proteins: haptocorrin, intrinsic factor, and transcobalamin. The nature of cobalamin-binding proteins in lower vertebrates remains to be elucidated.
Højrup, Peter +7 more
core +1 more source