Results 101 to 110 of about 901 (171)

Differential Influence of the Antiretroviral Pharmacokinetic Enhancers Ritonavir and Cobicistat on Intestinal P-Glycoprotein Transport and the Pharmacokinetic/Pharmacodynamic Disposition of Dabigatran

, 2017
Dabigatran etexilate (DE) is a P-glycoprotein (P-gp) probe substrate, and its active anticoagulant moiety, dabigatran, is a substrate of the multidrug and toxin extrusion protein-1 (MATE-1) transporter.
Parag Kumar, Lori A. Gordon, Raul M. Alfaro, Colleen Hadigan, Maryellen McManus, Khanh Nghiem, Anela Kellogg, Scott R. Penzak, Jomy M. George, Kristina M. Brooks, Jay Lozier   +10 more
core   +1 more source

Switch to bictegravir/emtricitabine/tenofovir alafenamide in people living with HIV aged 65 years or older: BICOLDER study – IMEA 057

Journal of Infection and Public Health
Background: Polymedication and comorbidities are frequent in aging people with HIV (PWH) and often associated with elevated incidences of adverse events (AEs) and drug-drug interactions (DDIs).
Minh P. Lê, Clotilde Allavena, Véronique Joly, Lambert Assoumou, Valentina Isernia, Faiza Ajana, Didier Neau, Diane Descamps, Charlotte Charpentier, Aïda Benalycherif, Bao Phung, Gilles Peytavin, Roland Landman   +12 more
doaj   +1 more source

Darunavir/Cobicistat [PDF]

, 2020
openaire   +1 more source

Elvitegravir/cobicistat-associated toxic optical neuropathy in an HIV-infected patient: a call for caution?

, 2017
Ocular toxicity may not only be caused by medication overdoses and drug-drug interactions, but also by the chronic administration of medications at recommended doses.
A. Invernizzi, C. Gervasoni, D. Cattaneo, V. Micheli, A. Riva, RESNATI, CHIARA   +5 more
core   +1 more source

Concentration-time profiles for the accumulation of elvitegravir in U1 cells with or without cobicistat and ethanol.

, 2017
Results expressed as means ± SEM of the cellular concentrations measured (μM/mg of protein). EVG, Elvitegravir; COBI, Cobicistat; EtOH, ethanol.
Pradeep B. Lukka (3775327), Santosh Kumar (106550), Bernd Meibohm (110267), Narasimha M. Midde (309014), Namita Sinha (724836)   +4 more
core   +1 more source

Synergistic antifungal activity of antiretrovirals with amphotericin B against Aspergillus species.

PLoS ONE
Aspergillosis is a life-threatening fungal infection that primarily affects the lungs of immunocompromised individuals, including those living with human immunodeficiency virus (HIV), and is associated with mortality rates exceeding 50%. The infection is
Ammar A Khan, Ehab A Salama, Mohamed N Seleem   +2 more
doaj   +1 more source

Atazanavir/Cobicistat [PDF]

, 2020
openaire   +1 more source

Profile of once-daily darunavir/cobicistat fixed-dose combination for the treatment of HIV/AIDS

Altres ajuts: AC has received honoraria, speakers' fees and/or funds for research from Bristol-Myers Squibb, Abbvie, Gilead Sciences, Janssen-Cilag, MSD, and ViiV Healthcare. JN has received honoraria, speakers' fees and/or funds for research from Abbvie,
Curran, Adrian, Navarro, Jordi, Universitat Autònoma de Barcelona   +2 more
core  

Kinetic Characterization of elvitegravir (EVG) in the presence and absence of cobicistat (COBI) and/or ethanol (EtOH)

, 2016
Kinetic Characterization of elvitegravir (EVG) in the presence and absence of cobicistat (COBI) and/or ethanol (EtOH)
Mohammad A. Rahman (1806823), Chetan Rathi (1806826), Weihua Li (144468), Santosh Kumar (106550), Bernd Meibohm (110267), Junhao Li (844050), Narasimha M. Midde (309014)   +6 more
core  

UPLC SEPARATION ANALYSIS OF EMTRICITABINE, TENOFOVIR, COBICISTAT AND ELVITEGRAVIR FROM THEIR DEGRADATION PRODUCTS

, 2016
Objective: A simple, rapid, accurate and precise stability-indicating UPLC analytical method has been developed and validated for the quantitative analysis of Emtricitabine, Tenofovir, Cobicistat and Elvitegravir in bulk drugs and combined dosage forms ...
P., Prahlad, N., Ravindra, S. K., Mastanamma, Rao M., Venkata Basaveswara, P., Revathi Naga Lakshmi   +4 more
core