The Assessment of the Degree of Concordance Between the Observed Values and the Predicted Values of a Mixed-Effect Model Using “Method of Comparison” Techniques [PDF]
In this paper, we present a methodology for determining the degree of concordance between observed and model-based predicted values of a mixed-effect model.
Guo, Nan, McCarthy, William F.
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RSEA: A Web Server for Pathway Enrichment Analysis of Metabolic Reaction Sets
Reaction Set Enrichment Analysis (RSEA), a web server tool designed for metabolic pathway enrichment analysis of reaction sets derived from genome‐scale metabolic models was introduced. RSEA converts given reaction lists into standardized identifiers and statistically evaluates their enrichment across metabolic pathways.
Merve Yarıcı+4 more
wiley +1 more source
Insights on Scan‐Specific Deep‐Learning Strategies for Brain MRI Parallel Imaging Reconstruction
Methods are proposed to optimize 2D brain MRI parallel imaging reconstruction using scan‐specific deep learning strategies. The study challenges the use of neural networks trained with limited ACS data and larger acceleration rates than clinical practice, notably proposing a new image metrics sensitive to structured residual artifacts to select models.
Swetali Nimje+3 more
wiley +1 more source
On ‘Cobric Acid’, a so‐called Constituent of Cobra Venom [PDF]
R. Norris Wolfenden
openalex +1 more source
Semi-Parametrics Dose Finding Methods [PDF]
We describe a new class of dose finding methods to be used in early phase clinical trials. Under some added parametric conditions the class reduces to the family of continual reassessment method (CRM) designs.
Clertant, Matthieu, O\u27Quigley, John
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ABSTRACT Roots located in the upper soil layers are prone to experiencing high temperatures. Despite their importance for water and nutrient absorption, little is known about the effect of high temperature on root hairs. Here, we found that exposure of Arabidopsis thaliana seedlings to long‐term mild heat suppressed root hair initiation.
Gaigai Du+5 more
wiley +1 more source
An Example of How to Write the Statistical Section of a Bioequivalence Study Protocol for FDA Review [PDF]
This paper provides a detailed example of how one should write the statistical section of a bioequivalence study protocol for FDA review. Three forms of bioequivalence are covered: average bioequivalence (ABE), population bioequivalence (PBE) and ...
McCarthy, William F.
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Impact of racialization on neuroimaging and plasma biomarkers of Alzheimer's disease
Abstract INTRODUCTION Given the predominance of imaging and plasma biomarkers in Alzheimer's disease observational studies and clinical trials, it is critical to understand the differences between these biomarkers across racialized groups. METHODS A total of 260 older adults without dementia racialized as Black and/or African American (AA) and non ...
Alexandra Gogola+19 more
wiley +1 more source
Electrochemical Hydrosilylation of Alkynes
Tony Biremond+2 more
doaj +1 more source
A Simple Method to Estimate the Time-dependent ROC Curve Under Right Censoring [PDF]
The time-dependent Receiver Operating Characteristic (ROC) curve is often used to study the diagnostic accuracy of a single continuous biomarker, measured at baseline, on the onset of a disease condition when the disease onset may occur at different ...
Greene, Tom, Hu, Bo, Li, Liang
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