Nicotine and/or Cocaine Alters Postnatal Ventilatory Control in the Rat Pup Gestationally Exposed [PDF]
, 1999 Jeannine L. Gingras +3 more
openalex +1 more source
A multi-site, double-blind, placebo-controlled pilot clinical trial to evaluate the efficacy of buspirone as a relapse-prevention treatment for cocaine dependence [PDF]
, 2014 Objective—To evaluate the potential efficacy of buspirone as a relapse-prevention treatment for cocaine dependence. Method—A randomized, double-blind, placebo-controlled, 16-week pilot trial conducted at six clinical sites between August 2012 and June ...
Chartier, Karen G. +6 more
core +1 more source
Characteristics of methamphetamine‐related deaths in the United Kingdom, 1997–2024
Addiction, EarlyView.Abstract Background and aims People who use methamphetamine have a standardised mortality ratio 6.8 times greater than the general population, with several countries reporting concerning increases in methamphetamine‐related mortality over the past decade.
Emmert Roberts +2 more
wiley +1 more source
Chronic cocaine enhances release of neuroprotective amino acid taurine: a microdialysis study [PDF]
, 2008 Cocaine inhibits high-affinity neurotransmitter uptake at the presynaptic nerve terminals to increase synaptic levels of dopamine, norepinephrine and serotonin^1^. This increase of synaptic dopamine may cause neurotoxicity^2,3^.
Eitan Freedman +5 more
core +1 more source
Addiction, EarlyView.Abstract Background and aims Substance use and other addictive behaviours including gambling remain major public health concerns in the UK. Despite the effectiveness of substance use treatment approaches, treatment adherence and success rates remain low.
Carol‐Ann Getty +2 more
wiley +1 more source
Drug use among people in prison: A global review of epidemiology, harms and interventions
Addiction, EarlyView.Abstract Background and aims People who use drugs are overrepresented in the criminal justice system. We aimed to provide a broad synthesis of the epidemiology, harms and interventions related to drug use and drug use disorders among incarcerated adults worldwide, and highlight gaps in evidence and practice.
Louis Favril, John Strang, Seena Fazel
wiley +1 more source
Supply-side reduction policy and drug-related harm [PDF]
Large-scale seizures of cocaine, heroin and amphetamine-type substances (ATS) do not result in any reduction in overdoses on these drugs or on arrests for use and possession of these drugs, according to this report.
Don Weatherburn +4 more
core +1 more source
Exploring the genetic overlap between substance use disorder and educational attainment
Addiction, EarlyView.Abstract Background and aims Substance use disorder (SUD) is a polygenic psychiatric condition characterized by persistent drug use despite negative consequences. Several studies support that higher cognitive performance and educational attainment (EA) are associated with a reduced risk for SUD.
Judit Cabana‐Domínguez +16 more
wiley +1 more source
Chronic Cocaine Enhances Corticotropin-Releasing Factor-Dependent Potentiation of Excitatory Transmission in Ventral Tegmental Area Dopamine Neurons [PDF]
, 2009 Junghyun Hahn +2 more
openalex +1 more source
Rare but relevant: MDMA and hyponatraemia
Addiction, EarlyView.Abstract Conventionally used for its stimulant, empathogenic and entactogenic effects, 3,4‐methylenedioxymethamphetamine (MDMA, ecstasy) is one of the most commonly used psychoactive drugs, specifically among young adults and in nightlife and recreational party contexts.
Maria Rita Garcia +2 more
wiley +1 more source