Results 121 to 130 of about 163,677 (304)
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Introduction Suicidal ideation and behaviors (SIB) are common among individuals at clinical high risk for psychosis (CHR‐P), but their relationship with the overall clinical profile remains unclear. This study aimed to identify sociodemographic/clinical factors associated with SIB in CHR‐P individuals and to examine whether subthreshold ...
Stefano Damiani +73 more
wiley +1 more source
The Neuroscience Of Cocaine: Mechanisms And Treatment
, 2016 The fundamental role of D-serine as co-agonist at the N-methyl-D-aspartate receptor (NMDAR), a major glutamate receptor subtype involved in synaptic plasticity, is well documented and experimental evidence indicates now that this D-amino acid is an ...
Mainardi, Marco +2 more
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, 2016 Cocaine-and Amphetamine Regulated Transcript (CART) Peptide Is Expressed in Precursor Cells and Somatotropes of the Mouse Pituitary Gland - Table
Sally A. Camper (41538) +1 more
core +1 more source
Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review
Addiction, EarlyView.Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper +7 more
wiley +1 more source
Myocardial damage post short-term self-administration cocaine usage in rat
Journal of Molecular and Cellular Cardiology PlusCocaine abuse remains a significant risk with profound adverse impact on cardiovascular health. While long-term cocaine addiction-induced cardiotoxicity is well-documented, the underlying mechanism and the molecular effects of short-term recreational ...
Muhammad Zubair Saleem +4 more
doaj +1 more source
Alcohol makes rats more likely to compulsively take cocaine.
, 2017 Results from the us study suggest alcohol increases compulsive cocaine use by promoting the breakdown of important proteins in the nucleus accumbens, a brain region critical for reward-based memory....
Hosford, Paul
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Addiction, EarlyView.Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens +7 more
wiley +1 more source
, 2010 Background: Cocaine- and amphetamine-regulated transcript (CART) has been demonstrated to play a role in regulating the rewarding and reinforcing effects of various drugs of abuse. A recent study demonstrated that i.c.v. administration of CART negatively
Janine Charnley (21137000) +7 more
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Addiction, EarlyView.Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden +10 more
wiley +1 more source
Pneumomediastinum after cocaine use: an unusual aetiology
, 2010 We describe an interesting case of pneumomediastinum secondary to cocaine abuse. The patient presented with severe chest pain following nasal inhalation of a large quantity of cocaine.
Gourevitch D, Seenath M, Chudasama K
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