Results 131 to 140 of about 307,196 (303)
The association of methadone use with physical function and frailty among persons who inject drugs
Addiction, EarlyView.Abstract Background and Aims Persons who inject drugs (PWID) experience a high burden of early‐onset frailty, primarily due to multifactorial causes such as infections (human immunodeficiency virus [HIV], hepatitis C virus [HCV]), substance use, and polypharmacy.
Grace L. Kulik +10 more
wiley +1 more source
Effects of palmitoylethanolamide in cocaine-induced behaviours [PDF]
, 2016 Aims. Cocaine addiction is a chronically relapsing disorder characterized by the compulsion to seek and take the drug. Previous investigations have demonstrated that several drugs of abuse, as cocaine, can alter the levels of lipid-based signalling ...
Blanco, Eduardo +7 more
core
Addiction‐related problems in Japan: A regional perspective
Addiction, EarlyView.Abstract Japan's addiction landscape appears paradoxical. The lifetime use of illicit drugs is among the lowest in Organisation for Economic Cooperation and Development countries, but harm from alcohol, tobacco, and gambling ranks among the world's highest.
Soichiro Ide +19 more
wiley +1 more source
Time-Dependent Effects of Stress on Cocaine Conditioned Place Preference Using a Rat Model of Posttraumatic Stress Disorder [PDF]
, 2011 Posttraumatic Stress Disorder (PTSD) affects approximately 8% of the entire population within their lifetimes. A startling trend of co-occurring PTSD and cocaine use has surfaced among humans who express these disorders.
Helpenstell, Lily K.
core +1 more source
Addiction, EarlyView.Abstract Background and aims Tobacco smoking is a major risk factor for cardiovascular and lung diseases. A better understanding of its neurobiological underpinnings will benefit the prevention of smoking‐related illnesses and mortality. Previous studies link smoking to increased iron concentration in the striatum, a central component of the brain's ...
Olga Trofimova +2 more
wiley +1 more source
Trends in fentanyl‐containing drug samples seized by law enforcement agencies across Canada
Addiction, EarlyView.Abstract Background and aims Canada's drug toxicity crisis has been largely attributed to a volatile fentanyl‐dominated unregulated drug supply with increasing reports of fentanyl detected in combination with benzodiazepines, stimulants and xylazine.
Shaleesa Ledlie +6 more
wiley +1 more source
Addiction, EarlyView.Abstract Revived interest in psychedelic‐assisted therapies has also renewed focus on ibogaine, a psychoactive alkaloid, for its notable anti‐addictive potential. Evidence from observational, open‐label, and limited randomized placebo‐controlled trials indicates that ibogaine and its metabolite noribogaine reduce craving and withdrawal symptoms in ...
Tibor Markus Brunt
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy +11 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims There are currently no brief quantitative assessments that capture the drug patterns of people who engage in use of more than one drug on the same day or simultaneously. The current study examined the retest reliability, acceptability and feasibility of a new quantitative assessment to measure polysubstance use.
Amanda M. Bunting +7 more
wiley +1 more source