Transcriptional regulation of ventral hippocampus-nucleus accumbens circuit excitability drives cocaine seeking. [PDF]
Eagle AL +13 more
europepmc +1 more source
Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck +1 more
wiley +1 more source
Around two false equations: good cocaine, good cocaine; bad cocaine bad cocaine
El descubrimiento y la conquista de América no fue solo un choque armado, un encuentro de hombres, una confrontación de culturas y civilizaciones, sino también un intercambio de plantas y de animales: durante todo el siglo XVI (el proceso, por otro lado, continuará hasta hoy) en el Oceáno Atlántico se cruzan caminos diametralmente opuestos que llevan ...
openaire +1 more source
From Neuroadaptation to Neuroprogression: Rethinking Chronic Cocaine Exposure Through a Model of Cocaine-Related Cerebropathy. [PDF]
Carbone MG +11 more
europepmc +1 more source
Comprehensive transduceromic profiling of NOP receptor ligands at different Gα subunits
Abstract Background and Purpose The nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP) is an opioid receptor family member with distinct pharmacology and broad therapeutic potential. NOP receptors regulate functions such as nociception, stress reactivity, reward, mood, autonomic tone, immunity and sleep/wake cycle.
Davide Malfacini +9 more
wiley +1 more source
Disruption of Dopamine Homeostasis by Psychostimulants. [PDF]
Torres J +3 more
europepmc +1 more source
ABSTRACT Research on inequalities in children's services in the UK highlights a lack of systematic data on parental demographics, obstructing analysis of structural factors influencing children's outcomes. Using Growing Up in Scotland, a nationally representative longitudinal child cohort study of children born in 2004–2005, we investigate social ...
Valeria Skafida +2 more
wiley +1 more source
Cocaine induced astrocytic activation was associated with its vasoconstricting effects independent of its neuronal effects in the prefrontal cortex. [PDF]
Liu Y +5 more
europepmc +1 more source
Cell Type-Specific Encoding of Cocaine-Conditioned Responses in the Lateral Preoptic Area. [PDF]
Mejaes JI +5 more
europepmc +1 more source

