Results 191 to 200 of about 112,229 (260)

The Hoechst Dye‐Binding RNA Aptamer Recognizes Its Ligand in a Highly Dynamic Fashion

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
The Hoechst–RNA aptamer binds a tert‐butyl containing derivative of the Hoechst dye. The study presented here shows that the interactions between the RNA and ligand are highly dynamic with the ligand occupying two overlapping binding sites. The interactions are explored using NMR spectroscopy and time‐resolved fluorescence.
Natasha M. Evans   +2 more
wiley   +1 more source

Innovative Nanomaterial‐Based Approaches for the Recognition of Amphetamine in Attention Deficit Hyperactivity Disorder Management

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT The rising incidence of amphetamine misuse, particularly in the context of attention deficit hyperactivity disorder treatment, underscores the urgent need for sensitive and effective detection methods. This review examines innovative nanomaterial‐based approaches for AMP detection, emphasizing their advantages over conventional analytical ...
Ilghar Zeinaly   +5 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Dried blood spot analysis in antidoping: Technical challenges, analytical advances, and future perspectives

open access: yesBulletin of the Korean Chemical Society, Volume 47, Issue 6, Page 674-688, June 2026.
Dried blood spot (DBS) analysis enables minimally invasive blood collection with strong analyte stability and simplified logistics, supporting anti‐doping applications beyond traditional matrices. Recent advances address hematocrit, volume variability, and matrix effects while expanding coverage to steroid esters, World Anti‐Doping Agency‐listed ...
Jihyun Yoon   +4 more
wiley   +1 more source

Chemical Straightening as a Source of Analytical Variability in Hair Testing: A Dual‐Analyte Case Report

open access: yesDrug Testing and Analysis, Volume 18, Issue 6, Page 771-776, June 2026.
Permanent chemical hair straightening was associated with analyte‐dependent changes in hair concentrations, showing increased endogenous GHB levels and decreased alprazolam concentrations after treatment. These results suggest that chemical hair straightening procedures may influence hair concentrations and should be considered when interpreting hair ...
Miriam Blanco‐Ces   +5 more
wiley   +1 more source

Cocaine remodels m<sup>6</sup>A RNA-dependent signaling to drive locomotor plasticity in <i>Drosophila melanogaster</i>. [PDF]

open access: yesFront Cell Neurosci
Filošević Vujnović A   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy