Results 41 to 50 of about 3,351 (172)

Characterizing Innate and Adaptive Immune Responses to vaccine strain Coccidioides posadasii (cts2/ard1/cts3Δ) [PDF]

, 2021
Coccidiomycosis, colloquially known as Valley fever and Desert fever, is a respiratory fungal disease caused by Coccidioides immitis and Coccidioides posadasii.
Diep, Anh Loan
core   +1 more source

Expert opinion on the identification, risk assessment, and mitigation of microorganisms and parasites relevant to xenotransplantation products from pigs

Xenotransplantation, Volume 30, Issue 5, September/October 2023., 2023
Abstract Xenotransplantation has the potential to address shortages of organs available for clinical transplantation, but concerns exist regarding potential risks posed by porcine microorganisms and parasites (MP) to the health of human recipients. In this study, a risk‐based framework was developed, and expert opinion was elicited to evaluate porcine ...
Huybert Groenendaal, Solenne Costard, Reid Ballard, Stephen Bienhoff, Diana C. Challen, Brandon J. Dominguez, Douglas R. Kern, Dan Miller, Jeske Noordergraaf, Larisa Rudenko, Henk‐Jan Schuurman, Tom Spizzo, Matthew Sturos, Bill Zollers, Jay A. Fishman   +14 more
wiley   +1 more source

Spatiotemporal analysis of lung immune dynamics in lethal <i>Coccidioides posadasii</i> infection. [PDF]

mBio
ABSTRACT Coccidioidomycosis, or Valley fever, is a lung disease caused by inhalation of Coccidioides fungi, prevalent in the Southwestern United States, Mexico, and parts of Central and South America.
Davalos OA, Sebastian A, Leon NF, Rangel MV, Miranda N, Murugesh DK, Phillips AM, Hoyer KK, Hum NR, Loots GG, Weilhammer DR.   +10 more
europepmc   +4 more sources

The Known Unknowns of the Immune Response to Coccidioides

Journal of Fungi, 2021
Coccidioidomycosis, otherwise known as Valley Fever, is caused by the dimorphic fungi Coccidioides immitis and C. posadasii. While most clinical cases present with self-limiting pulmonary infection, dissemination of Coccidioides spp. results in prolonged
Rebecca A. Ward, George R. Thompson, Alexandra-Chloé Villani, Bo Li, Michael K. Mansour, Marcel Wuethrich, Jenny M. Tam, Bruce S. Klein, Jatin M. Vyas   +8 more
doaj   +1 more source

Effective Disinfectants for Coccidioides Immitis and C. posadasii [PDF]

Applied Biosafety, 2015
The lack of published data on effective disinfectants and contact times for use on the fungal pathogens Coccidioides immitis and C. posadasii prompted the authors to investigate the fungicidal activity of three commonly used laboratory disinfectants on arthroconidia harvested from C. immitis strain 2009.
Amy J, Vogler, Roxanne, Nottingham, Katy L, Parise, Paul, Keim, Bridget M, Barker   +4 more
openaire   +2 more sources

Coccidioides Endospores and Spherules Draw Strong Chemotactic, Adhesive, and Phagocytic Responses by Individual Human Neutrophils. [PDF]

PLoS ONE, 2015
Coccidioides spp. are dimorphic pathogenic fungi whose parasitic forms cause coccidioidomycosis (Valley fever) in mammalian hosts. We use an innovative interdisciplinary approach to analyze one-on-one encounters between human neutrophils and two forms of
Cheng-Yuk Lee, George R Thompson, Christine J Hastey, Gregory C Hodge, Jennine M Lunetta, Demosthenes Pappagianis, Volkmar Heinrich   +6 more
doaj   +1 more source

A Metalloproteinase of Coccidioides posadasii Contributes to Evasion of Host Detection [PDF]

Infection and Immunity, 2005
ABSTRACT Coccidioides posadasii is a fungal respiratory pathogen of humans that can cause disease in immunocompetent individuals. Coccidioidomycosis ranges from a mild to a severe infection. It is frequently characterized either as a persistent disease that requires months to resolve or as an ...
Chiung-Yu, Hung, Kalpathi R, Seshan, Jieh-Juen, Yu, Ruth, Schaller, Jianmin, Xue, Venkatesha, Basrur, Malcolm J, Gardner, Garry T, Cole   +7 more
openaire   +2 more sources

Characterization of a Serodiagnostic Complement Fixation Antigen of Coccidioides posadasii Expressed in the Nonpathogenic Fungus Uncinocarpus reesii [PDF]

, 2005
Coccidioides spp. (immitis and posadasii) are the causative agents of human coccidioidomycosis. In this study, we developed a novel system to overexpress coccidioidal proteins in a nonpathogenic fungus, Uncinocarpus reesii, which is closely related to ...
Thomas, PW, Hung, C-Y, T. N. Kirkland, P. W. Thomas, C.-Y. Hung, J.-J. Yu, Chen, X, Hall, LK, L. K. Hall, G. T. Cole, Smith, RC, Cole, GT, Tarcha, E, Yu, J-J, J. Wopschall, Wopschall, J, R. C. Smith, E. Tarcha, Kirkland, TN, X. Chen   +19 more
core   +1 more source

The Characterization of Coccidioides posadasii During the Parasitic Life Stage [PDF]

, 2021
Coccidioides posadasii and Coccidioides immitus are both dimorphic fungal species responsible for the disease coccidioidomycosis known as Valley Fever. Located in the arid southwestern part of the United States, Coccidioides’ environmental form is found ...
Garcia, Javier Alejandro
core   +1 more source

Local Population Structure and Patterns of Western Hemisphere Dispersal for Coccidioides spp., the Fungal Cause of Valley Fever

mBio, 2016
Coccidioidomycosis (or valley fever) is a fungal disease with high morbidity and mortality that affects tens of thousands of people each year. This infection is caused by two sibling species, Coccidioides immitis and C.
David M. Engelthaler, Chandler C. Roe, Crystal M. Hepp, Marcus Teixeira, Elizabeth M. Driebe, James M. Schupp, Lalitha Gade, Victor Waddell, Kenneth Komatsu, Eduardo Arathoon, Heidi Logemann, George R. Thompson, Tom Chiller, Bridget Barker, Paul Keim, Anastasia P. Litvintseva   +15 more
doaj   +1 more source