Results 171 to 180 of about 107,745 (350)

Bilateral Carotid Artery Occlusion and Cochlear Oxidative Stress and Hearing Loss in Rats

open access: yesBasic and Clinical Neuroscience, 2020
Introduction: This study aimed to evaluate the effects of bilateral carotid artery occlusion on cochlear oxidative stress and hearing status in rats. Methods: The rats were divided into two sets. The first set was used for electrophysiological recording (
Hamed Fanaei   +2 more
doaj  

Deep Spiking Neural Network model for time-variant signals classification: a real-time speech recognition approach [PDF]

open access: yes, 2018
Speech recognition has become an important task to improve the human-machine interface. Taking into account the limitations of current automatic speech recognition systems, like non-real time cloud-based solutions or power demand, recent interest for
Davidson, Simón   +6 more
core  

Simultaneous encoding of sensory features: the role of multiplexing and noise in tactile perception and neural representation

open access: yesBiological Reviews, EarlyView.
ABSTRACT The nervous system's capacity to process complex stimuli has long intrigued neuroscientists, with multiplexing now recognized as a fundamental neural coding strategy. Multiplexing refers to the simultaneous encoding of multiple stimulus features via vi distinct components of neuronal responses, such as firing rates and precise temporal spike ...
Mohammad Amin Kamaleddin
wiley   +1 more source

Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BK-beta-1-subunit leads to progressive hearing loss [PDF]

open access: yes, 2005
The large conductance voltage- and Ca2+-activated potassium (BK) channel has been suggested to play an important role in the signal transduction process of cochlear inner hair cells.
Arntz, Claudia   +18 more
core  

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

open access: yesCell Proliferation, EarlyView.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang   +10 more
wiley   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

open access: yesCell Proliferation, EarlyView.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng   +4 more
wiley   +1 more source

Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma

open access: gold, 2014
Guoqiang Wan   +4 more
openalex   +2 more sources

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

open access: yesThe FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy