Otosclerosis under microCT: New insights into the disease and its anatomy
Frontiers in Radiology, 2022 PurposeOtospongiotic plaques can be seen on conventional computed tomography (CT) as focal lesions around the cochlea. However, the resolution remains insufficient to enable evaluation of intracochlear damage.
Gabriela O'Toole Bom Braga +5 more
doaj +1 more source
The endocannabinoid/cannabinoid receptor 2 system protects against cisplatin-induced hearing loss [PDF]
, 2018 Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells ...
Asmita Dhukhwa +8 more
core +4 more sources
Vibration hotspots reveal longitudinal funneling of sound-evoked motion in the mammalian cochlea
Nature Communications, 2018 The micromechanical mechanisms that underpin tuning and dynamic range compression in the mammalian inner ear are fundamental to hearing, but poorly understood.
N. Cooper +2 more
semanticscholar +1 more source
Inner-ear abnormalities and their functional consequences in Belgian Waterslager canaries (Serinus canarius) [PDF]
, 1994 Recent reports of elevated auditory thresholds in canaries of the Belgian Waterslager strain have shown that this strain has an inherited auditory deficit in which absolute auditory thresholds at high frequencies (i.e. above 2.0 kHz) are as much as 40 dB
Brown +42 more
core +1 more source
Alternative splicing in shaping the molecular landscape of the cochlea
Frontiers in Cell and Developmental Biology, 2023 The cochlea is a complex organ comprising diverse cell types with highly specialized morphology and function. Until now, the molecular underpinnings of its specializations have mostly been studied from a transcriptional perspective, but accumulating ...
Kwan Soo Kim +5 more
doaj +1 more source
In vivo genetic manipulation of inner ear connexin expression by bovine adeno-Associated viral vectors [PDF]
, 2017 We have previously shown that in vitro transduction with bovine adeno-associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin-deficient mice that are models DFNB1 ...
Campioni, Matteo +7 more
core +1 more source
The Development of a Single Frequency Place in the Mammalian Cochlea: The Cochlear Resonance in the Mustached Bat Pteronotus parnellii [PDF]
, 2003 Cochlear microphonic potentials (CMs) were recorded from the sharply tuned, strongly resonant auditory foveae of 1- to 5-week-old mustached bats that were anesthetized with Rompun and Ketavet.
Drexl, Markus +4 more
core +2 more sources
Efferent Inhibition of the Cochlea.
Cold Spring Harbor Perspectives in Medicine, 2018 Cholinergic efferent neurons originating in the brainstem innervate the acoustico-lateralis organs (inner ear, lateral line) of vertebrates. These release acetylcholine (ACh) to inhibit hair cells through activation of calcium-dependent potassium ...
P. Fuchs, Amanda M. Lauer
semanticscholar +1 more source
The cochlea as a smart structure [PDF]
Smart Materials and Structures, 2012 The cochlea is part of the inner ear and its mechanical response provides us with many aspects of our amazingly sensitive and selective hearing. The human cochlea is a coiled tube, with two main fluid chambers running along its length, separated by a 35 mm-long flexible partition that has its own internal dynamics. A dispersive wave can propagate along
Stephen J. Elliott +2 more
openaire +5 more sources