Results 41 to 50 of about 33,521 (228)

Expression and function of scleraxis in the developing auditory system.

PLoS ONE, 2013
A study of genes expressed in the developing inner ear identified the bHLH transcription factor Scleraxis (Scx) in the developing cochlea. Previous work has demonstrated an essential role for Scx in the differentiation and development of tendons ...
Zoe F Mann, Weise Chang, Kyu Yup Lee, Kelly A King, Matthew W Kelley   +4 more
doaj   +1 more source

An analog electronic cochlea [PDF]

IEEE Transactions on Acoustics, Speech, and Signal Processing, 1988
An analog electronic cochlea has been built in CMOS VLSI technology using micropower techniques. The key point of the model and circuit is that a cascade of simple, nearly linear, second-order filter stages with controllable Q parameters suffices to capture the physics of the fluid-dynamic traveling-wave system in the cochlea, including the effects of ...
Lyon, Richard F., Mead, Carver
openaire   +2 more sources

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

Advanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo, Shanshan Jiang, Yimian Luo, Adele Moatti, Farnaz Matin‐Mann   +4 more
wiley   +1 more source

A Case Study Assessing the Auditory and Speech Development of Four Children Implanted with Cochlear Implants by the Chronological Age of 12 Months

Case Reports in Otolaryngology, 2013
Children with severe hearing loss most likely receive the greatest benefit from a cochlear implant (CI) when implanted at less than 2 years of age. Children with a hearing loss may also benefit greater from binaural sensory stimulation. Four children who
Birgit May-Mederake, Wafaa Shehata-Dieler   +1 more
doaj   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Clinical Validation of Manual Measurement of Cochlea Length With Post‐Operative Electrode Insertion Depth: A Pilot Study

Laryngoscope Investigative Otolaryngology
Objective To clinically validate manual measurement of cochlear length from pre‐operative image of cochlea with post‐operative image of cochlear implant (CI) electrode.
Fei Wang, Dharmikkumar Anaghan, Anandhan Dhanasingh, Lian Hui   +3 more
doaj   +1 more source

Effect of Dielectric Properties of Cochlea on Electrode Insertion Guidance Based on Impedance Variation

Applied Sciences
The cochlear neuromodulator provides substantial auditory perception to those with impaired hearing. The accurate insertion of electrodes into the cochlea is an important factor, as misplaced may lead to further damage.
Enver Salkim
doaj   +1 more source

Deafness gene expression patterns in the mouse cochlea found by microarray analysis.

PLoS ONE, 2014
BackgroundTonotopy is one of the most fundamental principles of auditory function. While gradients in various morphological and physiological characteristics of the cochlea have been reported, little information is available on gradient patterns of gene ...
Hidekane Yoshimura, Yutaka Takumi, Shin-ya Nishio, Nobuyoshi Suzuki, Yoh-ichiro Iwasa, Shin-ichi Usami   +5 more
doaj   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Gap junction mediated intercellular metabolite transfer in the cochlea is compromised in connexin30 null mice. [PDF]

PLoS ONE, 2008
Connexin26 (Cx26) and connexin30 (Cx30) are two major protein subunits that co-assemble to form gap junctions (GJs) in the cochlea. Mutations in either one of them are the major cause of non-syndromic prelingual deafness in humans. Because the mechanisms
Qing Chang, Wenxue Tang, Shoeb Ahmad, Binfei Zhou, Xi Lin   +4 more
doaj   +1 more source