Results 51 to 60 of about 73,807 (263)

Relationship of glucocorticoid receptor expression in peripheral blood mononuclear cells and the cochlea of guinea pigs and effects of dexamethasone administration. [PDF]

PLoS ONE, 2013
BACKGROUND: Glucocorticoids (GCs) are widely used to treat sudden sensorineural hearing loss (SSNHL) and significantly improve hearing. However, GC insensitivity has been observed in some patients of SSNHL.
Ling Lu, Yanhong Dai, Xiaoping Du, Wandong She, Xiuling Zhang, Qin Wu, Wenjie Yuan, Feng Chen   +7 more
doaj   +1 more source

Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors [PDF]

, 2001
The deafness caused by early onset hypothyroidism indicates that thyroid hormone is essential for the development of hearing. We investigated the underlying roles of the TRa1 and TRß thyroid hormone receptors in the auditory system using receptor ...
Forrest, Douglas, Goodyear, Richard, Kelley, Matthew W, Lisoukov, Igor, Ng, Lily, Oliver, Dominik, Richardson, Guy, Rüsch, Alfons, Vennström, Björn   +8 more
core   +1 more source

The Green Cochlea

Brazilian Journal of Otorhinolaryngology
Healthcare systems contribute significantly to global greenhouse gas emissions through energy consumption and waste generation. This study aims to explore strategies to make cochlear implantation processes more environmentally sustainable and aligned with the United Nations' Sustainable Development Goals.We examined various approaches including the use
Abdulrahman Hagr, Farid Alzhrani, Fida Almuhawas, Yassin Abdelsamad, Medhat Yousef, Asma Alahmadi, Christiana Kyvelidou, Ilona Anderson   +7 more
openaire   +4 more sources

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

Expression and function of scleraxis in the developing auditory system.

PLoS ONE, 2013
A study of genes expressed in the developing inner ear identified the bHLH transcription factor Scleraxis (Scx) in the developing cochlea. Previous work has demonstrated an essential role for Scx in the differentiation and development of tendons ...
Zoe F Mann, Weise Chang, Kyu Yup Lee, Kelly A King, Matthew W Kelley   +4 more
doaj   +1 more source

Cooperativity of Kv7.4 channels confers ultrafast electromechanical sensitivity and emergent properties in cochlear outer hair cells. [PDF]

, 2020
The mammalian cochlea relies on active electromotility of outer hair cells (OHCs) to resolve sound frequencies. OHCs use ionic channels and somatic electromotility to achieve the process.
Chiamvimonvat, Nipavan, Kim, Hyo Jeong, Ledford, Hannah A, Lee, Jeong H, Park, Seojin, Perez-Flores, Maria C, Rabbitt, Richard D, Sihn, Choong-Ryoul, Timofeyev, Valeriy, Wang, Wenying, Yamoah, Ebenezer N, Yarov-Yarovoy, Vladimir, Zhang, Xiao-Dong   +12 more
core   +1 more source

An analog electronic cochlea [PDF]

IEEE Transactions on Acoustics, Speech, and Signal Processing, 1988
An analog electronic cochlea has been built in CMOS VLSI technology using micropower techniques. The key point of the model and circuit is that a cascade of simple, nearly linear, second-order filter stages with controllable Q parameters suffices to capture the physics of the fluid-dynamic traveling-wave system in the cochlea, including the effects of ...
Lyon, Richard F., Mead, Carver
openaire   +2 more sources

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science
The current understanding of the human auditory system has been primarily based on studies using animal and cellular models. Organoids have been used to simulate cochlear structures and replicate cochlear functions.
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
doaj   +1 more source

Culturing Neurons on MEMS Fabricated P(VDF-TrFE) Films for Implantable Artificial Cochlea

Journal of Biomechanical Science and Engineering, 2010
In this paper, we report an in vitro study on the biocompatibility of poly(vinylidene fluoride-trifluoroethylene) (P(VDF-TrFE)) films for the implantable artificial cochlea.
Hirofumi SHINTAKU, Takashi TATENO, Nobuyoshi TSUCHIOKA, Harto TANUJAYA, Takayuki NAKAGAWA, Juichi ITO, Satoyuki KAWANO   +6 more
doaj   +1 more source