Results 61 to 70 of about 73,190 (256)
Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss
Advanced Science, EarlyView.. ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao +9 more
wiley +1 more source
Deafness gene expression patterns in the mouse cochlea found by microarray analysis.
PLoS ONE, 2014 BackgroundTonotopy is one of the most fundamental principles of auditory function. While gradients in various morphological and physiological characteristics of the cochlea have been reported, little information is available on gradient patterns of gene ...
Hidekane Yoshimura +5 more
doaj +1 more source
Neuro-electronic technology in medicine and beyond [PDF]
, 2000 This dissertation looks at the technology and social issues involved with interfacing electronics directly to the human nervous system, in particular the methods for both reading and stimulating nerves.
Ward, Jamie A
core
Cochlear-bone wave can yield a hearing sensation as well as otoacoustic emission
, 2014 A hearing sensation arises when the elastic basilar membrane inside the cochlea vibrates. The basilar membrane is typically set into motion through airborne sound that displaces the middle ear and induces a pressure difference across the membrane.
Reichenbach, T., Tchumatchenko, T.
core +1 more source
Dosimetric Analysis of Neural and Vascular Structures in Skull Base Tumors Treated with Stereotactic Radiosurgery. [PDF]
, 2017 Objective To examine the relationship between the prescribed target dose and the dose to healthy neurovascular structures in patients with vestibular schwannomas treated with stereotactic radiosurgery (SRS).
Bhatt, Jay M +6 more
core +1 more source
Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies
Animal Models and Experimental Medicine, EarlyView.This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang +4 more
wiley +1 more source
Laryngoscope Investigative OtolaryngologyObjective To clinically validate manual measurement of cochlear length from pre‐operative image of cochlea with post‐operative image of cochlear implant (CI) electrode.
Fei Wang +3 more
doaj +1 more source
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation [PDF]
, 2006 The planar cell polarity (PCP) pathway is conserved throughout evolution, but it mediates distinct developmental processes. In Drosophila, members of the PCP pathway localize in a polarized fashion to specify the cellular polarity within the plane of the
Brinkman, Brendan C. +9 more
core +1 more source
The Anatomical Record, EarlyView.Abstract The oval window (OW) is an opening connecting the inner and middle ear. Its area has been shown to consistently scale with body mass (BM) in primates, and has been used alongside semi‐circular canal (SCC) size to differentiate Homo sapiens and fossil hominins, including Paranthropus robustus.
Ruy Fernandez, José Braga
wiley +1 more source
Developmental expression of inositol 1, 4, 5-trisphosphate receptor in the post-natal rat cochlea
European Journal of Histochemistry, 2015 Inositol 1, 4, 5-trisphosphate receptor (IP3R) has been established to be essential for hearing. However, the expression of IP3R in the cochlea in the period of auditory development remains unknown.
W.J. Liu, J. Yang
doaj +1 more source