Results 81 to 90 of about 34,661 (220)

The cochlea [PDF]

open access: yesCurrent Biology, 2000
Ashmore, Jonathan, Gale, Jonathan
openaire   +2 more sources

Impact of Intraoperative Patient‐Specific 3D‐Printed Temporal Bones: A Randomized Controlled Trial

open access: yesThe Laryngoscope, EarlyView.
This randomized controlled trial demonstrates that inspecting patient‐specific 3D‐printed temporal bone models during cochlear implantation impacts cognitive load differently depending on surgical roles. We found models act as a cognitive offloading tool that reduces fatigue for attending surgeons, whereas they function as an active educational ...
Adam Omari   +3 more
wiley   +1 more source

Fast Waves at the Base of the Cochlea.

open access: yesPLoS ONE, 2015
Georg von Békésy observed that the onset times of responses to brief-duration stimuli vary as a function of distance from the stapes, with basal regions starting to move earlier than apical ones.
Alberto Recio-Spinoso, William S Rhode
doaj   +1 more source

Rapid Postmortem Temporal Bone Extraction and Dissection of Human Inner Ear Organs From Organ Donors

open access: yesThe Laryngoscope, EarlyView.
We developed a postmortem protocol for temporal bone extraction and dissection in organ donors, enabling atraumatic bilateral temporal bone retrieval within 1–2 h of ischemia, followed by stepwise microsurgical dissection of neurosensory organs. Combining rapid extraction, abbreviated decalcification, and atraumatic microsurgical dissection, this ...
Yassine Balhi   +10 more
wiley   +1 more source

Extraintestinal Manifestation of Crohn's Disease in the Middle Ear—A Case Report

open access: yesThe Laryngoscope, EarlyView.
A unique clinical case with extraintestinal manifestation of Crohn's disease in the middle ear, causing severe inflammation and troublesome symptoms. The combination of systemic therapy and surgery curbed the middle ear manifestation upon diagnosis.
Julia Arebro
wiley   +1 more source

Intracochlear PLGA based implants for dexamethasone release: Challenges and solutions

open access: yesInternational Journal of Pharmaceutics: X, 2019
The effective treatment of diseases of the inner ear is currently an unmet medical need. Local controlled drug delivery to the cochlea is challenging due to the hidden location, small volume and high sensitivity of this organ.
E. Lehner   +4 more
doaj   +1 more source

EHR‐Integrated Synoptic Operative Reporting for Head and Neck Oncologic Surgery

open access: yesThe Laryngoscope, EarlyView.
EHR‐integrated synoptic operative templates for head and neck oncologic surgery was developed and implemented at a tertiary academic cancer center. Departmental adherence rose from 49% to nearly 80% over 6 months, and 94.5% of reviewed cases met targets for complete, internally consistent documentation. The resulting structured data dictionary provides
Miriam N. Lango   +14 more
wiley   +1 more source

Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner.

open access: yesPLoS Genetics, 2019
The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation.
Lu M Yang   +3 more
doaj   +1 more source

Cochlear Implants for Radiation‐Induced Hearing Loss in Nasopharyngeal Cancer: A Systematic Review

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objectives To evaluate the safety and efficacy of cochlear implantation for auditory rehabilitation in patients with nasopharyngeal carcinoma (NPC) after radiation. Data Sources CINAHL, Cochrane Library, PubMed, and Scopus were searched from inception through February 2026.
Kaitlyn A. Roberts   +7 more
wiley   +1 more source

Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract The FDA approval of Otarmeni, an AAV‐based gene therapy for biallelic OTOF‐associated sensorineural hearing loss, represents a conceptual shift in otology: from bypassing defective auditory physiology to restoring it. Unlike cochlear implantation, which circumvents damaged sensory structures, OTOF gene replacement targets a synaptic deficit in
Jazlyn A. Selvasingh, Justin R. Shinn
wiley   +1 more source

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