Results 21 to 30 of about 34,661 (220)

Modeling cochlear micromechanics: hypotheses and models

open access: yesJournal of Bio-X Research, 2019
. The cochlea plays an important role in the mammalian auditory system. Sound-induced cell motion in the cochlea is transformed into electrical signals that are then sent to primary auditory neurons.
Guangjian Ni   +6 more
doaj   +1 more source

Microstructural interactions contribute to the hotspot in the living cochlea

open access: yesCurrent Research in Neurobiology, 2022
The mechanism of the active cochlea relies on a complex interaction between microstructures in the organ of Corti. A significant longitudinal vibration “hotspot” was recently observed in the high-frequency region of the living gerbil cochlea between the ...
Junpei Liu   +5 more
doaj   +1 more source

EXFOLIATION OF THE COCHLEA. [PDF]

open access: yesThe Lancet, 1898
n ...
openaire   +1 more source

Drug distribution along the cochlea is strongly enhanced by low-frequency round window micro vibrations

open access: yesDrug Delivery, 2021
The cochlea’s inaccessibility and complex nature provide significant challenges to delivering drugs and other agents uniformly, safely and efficiently, along the entire cochlear spiral. Large drug concentration gradients are formed along the cochlea when
Samuel M. Flaherty   +2 more
doaj   +1 more source

Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants

open access: yesFrontiers in Molecular Neuroscience, 2021
Optogenetic stimulation of type I spiral ganglion neurons (SGNs) promises an alternative to the electrical stimulation by current cochlear implants (CIs) for improved hearing restoration by future optical CIs (oCIs).
Antoine Tarquin Huet   +13 more
doaj   +1 more source

Regenerative Effect of a ROCK Inhibitor, Y-27632, on Excitotoxic Trauma in an Organotypic Culture of the Cochlea

open access: yesFrontiers in Cellular Neuroscience, 2020
In the past, most inner ear diseases were thought to start with the impairment of the sensory epithelium of the cochlea before subsequently progressing to secondary neural degeneration.
Yutaka Koizumi   +3 more
doaj   +1 more source

Analysis of a Dynamic Response of the Cochlea Using Fluid-Structure Interaction Model

open access: yesEngineering Transactions, 2016
A one-dimensional (1D) model of the cochlea of the inner ear has been built and validated against the previously built three-dimensional (3D) fluid-structure interaction (FSI) model of the cochlea.
Konrad KAMIENIECKI   +2 more
doaj   +1 more source

Analysis of Pharmacokinetics in the Cochlea of the Inner Ear

open access: yesFrontiers in Pharmacology, 2021
Hearing loss affects >5% of the global population and therefore, has a great social and clinical impact. Sensorineural hearing loss, which can be caused by different factors, such as acoustic trauma, aging, and administration of certain classes of ...
Seishiro Sawamura   +20 more
doaj   +1 more source

The Mechanism of the Cochlea [PDF]

open access: yesNature, 1922
IF I understand Dr. Perrett's letter in NATURE of November 11, p. 633, his objection to Yoshii's experiments (which would apply equally to those of Wittmaack and Siebenmann) is based on the assumption that the intensity of the stimulation of every part of the cochlea must be proportional to the amplitude of the vibration set up in that part.
openaire   +2 more sources

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