Results 11 to 20 of about 73,190 (256)

Mechanisms of sensorineural cell damage, death and survival in the cochlea. [PDF]

open access: yes, 2015
The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ryan, Allen F, Wong, Ann CY
core   +1 more source

The Active Traveling Wave in the Cochlea [PDF]

open access: yes, 2003
A sound stimulus entering the inner ear excites a deformation of the basilar membrane which travels along the cochlea towards the apex. It is well established that this wave-like disturbance is amplified by an active system.
D. D. Greenwood   +15 more
core   +2 more sources

The role of external broadcasting in a closed political system [PDF]

open access: yes, 2011
This article investigates the role and impact of external broadcasting (radio and television) on a closed political system, through the example of the two post-war German states: the West German Federal Republic of Germany (FRG) and the East German ...
Andreas Scheu   +23 more
core   +2 more sources

Auditory power-law activation-avalanches exhibit a fundamental computational ground-state [PDF]

open access: yes, 2016
The cochlea provides a biological information-processing paradigm that we only begin to under- stand in its full complexity. Our work reveals an interacting network of strongly nonlinear dynami- cal nodes, on which even simple sound input triggers ...
Gomez, Florian, Stoop, Ruedi
core   +1 more source

Drug distribution along the cochlea is strongly enhanced by low-frequency round window micro vibrations

open access: yesDrug Delivery, 2021
The cochlea’s inaccessibility and complex nature provide significant challenges to delivering drugs and other agents uniformly, safely and efficiently, along the entire cochlear spiral. Large drug concentration gradients are formed along the cochlea when
Samuel M. Flaherty   +2 more
doaj   +1 more source

Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants

open access: yesFrontiers in Molecular Neuroscience, 2021
Optogenetic stimulation of type I spiral ganglion neurons (SGNs) promises an alternative to the electrical stimulation by current cochlear implants (CIs) for improved hearing restoration by future optical CIs (oCIs).
Antoine Tarquin Huet   +13 more
doaj   +1 more source

E-ABR in patients with cochlear implant: A comparison between patients with malformed cochlea and normal cochlea [PDF]

open access: yes, 2019
OBJECTIVES: This study aims to compare the electrical auditory brainstem response (EABR) following cochlear implant (CI) surgery in pediatric subjects with cochlear malformation and a normal cochlea, in order to assess the sensitivity of EABR and to ...
de Lucia A.   +7 more
core   +1 more source

Regenerative Effect of a ROCK Inhibitor, Y-27632, on Excitotoxic Trauma in an Organotypic Culture of the Cochlea

open access: yesFrontiers in Cellular Neuroscience, 2020
In the past, most inner ear diseases were thought to start with the impairment of the sensory epithelium of the cochlea before subsequently progressing to secondary neural degeneration.
Yutaka Koizumi   +3 more
doaj   +1 more source

Analysis of Pharmacokinetics in the Cochlea of the Inner Ear

open access: yesFrontiers in Pharmacology, 2021
Hearing loss affects >5% of the global population and therefore, has a great social and clinical impact. Sensorineural hearing loss, which can be caused by different factors, such as acoustic trauma, aging, and administration of certain classes of ...
Seishiro Sawamura   +20 more
doaj   +1 more source

Analysis of a Dynamic Response of the Cochlea Using Fluid-Structure Interaction Model

open access: yesEngineering Transactions, 2016
A one-dimensional (1D) model of the cochlea of the inner ear has been built and validated against the previously built three-dimensional (3D) fluid-structure interaction (FSI) model of the cochlea.
Konrad KAMIENIECKI   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy