Results 11 to 20 of about 73,807 (263)
Development of the cochlea [PDF]
Development, 2020 ABSTRACT The cochlea, a coiled structure located in the ventral region of the inner ear, acts as the primary structure for the perception of sound. Along the length of the cochlear spiral is the organ of Corti, a highly derived and rigorously patterned sensory epithelium that acts to convert auditory stimuli into neural impulses.
Elizabeth Carroll Driver +1 more
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Mechanisms of sensorineural cell damage, death and survival in the cochlea. [PDF]
, 2015 The majority of acquired hearing loss, including presbycusis, is caused by irreversible damage to the sensorineural tissues of the cochlea. This article reviews the intracellular mechanisms that contribute to sensorineural damage in the cochlea, as well ...
Ryan, Allen F, Wong, Ann CY
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Modeling cochlear micromechanics: hypotheses and models
Journal of Bio-X Research, 2019 . The cochlea plays an important role in the mammalian auditory system. Sound-induced cell motion in the cochlea is transformed into electrical signals that are then sent to primary auditory neurons.
Guangjian Ni +6 more
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The Active Traveling Wave in the Cochlea [PDF]
, 2003 A sound stimulus entering the inner ear excites a deformation of the basilar membrane which travels along the cochlea towards the apex. It is well established that this wave-like disturbance is amplified by an active system.
D. D. Greenwood +15 more
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The Journal of Neuroscience, 1992 Peter Dallas Auditory Physiology Laboratory (The Hugh Knowles Center) and Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois 60208 The cochlea is a hydromechanical frequency analyzer located in the inner ear (Fig. 1 a).
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Drug Delivery, 2021 The cochlea’s inaccessibility and complex nature provide significant challenges to delivering drugs and other agents uniformly, safely and efficiently, along the entire cochlear spiral. Large drug concentration gradients are formed along the cochlea when
Samuel M. Flaherty +2 more
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Frontiers in Molecular Neuroscience, 2021 Optogenetic stimulation of type I spiral ganglion neurons (SGNs) promises an alternative to the electrical stimulation by current cochlear implants (CIs) for improved hearing restoration by future optical CIs (oCIs).
Antoine Tarquin Huet +13 more
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E-ABR in patients with cochlear implant: A comparison between patients with malformed cochlea and normal cochlea [PDF]
, 2019 OBJECTIVES: This study aims to compare the electrical auditory brainstem response (EABR) following cochlear implant (CI) surgery in pediatric subjects with cochlear malformation and a normal cochlea, in order to assess the sensitivity of EABR and to ...
de Lucia A. +7 more
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A Comprehensive Three-Dimensional Model of the Cochlea [PDF]
, 2003 The human cochlea is a remarkable device, able to discern extremely small amplitude sound pressure waves, and discriminate between very close frequencies.
Allaire +46 more
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Analysis of Pharmacokinetics in the Cochlea of the Inner Ear
Frontiers in Pharmacology, 2021 Hearing loss affects >5% of the global population and therefore, has a great social and clinical impact. Sensorineural hearing loss, which can be caused by different factors, such as acoustic trauma, aging, and administration of certain classes of ...
Seishiro Sawamura +20 more
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