Results 151 to 160 of about 17,452 (262)

Gene therapy for hereditary deafness: Progress, challenges and translational implications from OTOF to GJB2

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Current Management & Limitations: Traditional auditory devices lack genetic curative potential and yield variable, non‐physiological hearing outcomes. OTOF gene therapy has shown promising clinical outcomes with dual‐AAV therapy. GJB2 gene therapy remains an emerging approach with significant translational challenges. Advances in vector design and cell‐
Jiahui Zhao, Mengzhao Xun, Yu Sun
wiley   +1 more source

The National Health and Medical Research Council Research Impact Indicators: Unveiling Omissions and Blind Spots, and Positioning for Change

open access: yesHealth Promotion Journal of Australia, Volume 37, Issue 4, October 2026.
ABSTRACT Issue Addressed This study assesses how the concept of (health) research impact has been operationalised in National Health and Medical Research Council (NHMRC) Impact Case Studies, and if and how lived experience research priorities have been considered, to ascertain implications for Australian health and medical research.
Nizam Abdu   +6 more
wiley   +1 more source

Longitudinal Cochlear Implant Use in Pediatric Patients With Unilateral Hearing Loss. [PDF]

open access: yesOtolaryngol Head Neck Surg
Octeau D   +5 more
europepmc   +1 more source

Ménière's Disease: A Tri‐Decade Scoping Review of Treatment Trends and Evidence Quality

open access: yesThe Laryngoscope, Volume 136, Issue 10, Page 4482-4488, October 2026.
This tri‐decade scoping review of Ménière's disease literature reveals a significant increase in high‐level evidence and a clinical pivot toward hearing‐preserving interventions, such as intratympanic steroids and cochlear implants. However, a significant quality paradox has emerged, where adherence to standardized AAO‐HNS reporting and diagnostic ...
Ofir Zavdy   +4 more
wiley   +1 more source

Partitioned Internal Auditory Canal: Association With Cochlear Aperture Anomalies

open access: yesThe Laryngoscope, Volume 136, Issue 10, Page 4416-4423, October 2026.
Partitioned internal auditory canal (IAC), defined by a bony septum separating the facial nerve from the cochleovestibular nerve, occurs significantly more often in ears with stenotic or atretic cochlear aperture. ABSTRACT Objective To investigate the association between partitioned internal auditory canal (IAC) and other inner ear abnormalities ...
Levent Sennaroğlu, Emel Tahir
wiley   +1 more source

Synchrotron‐Based Deep Learning Network of the Inner Ear: Development and Expert Validation

open access: yesThe Laryngoscope, Volume 136, Issue 10, Page 4209-4218, October 2026.
A deep learning network to automatically segment the inner ear from preoperative clinical scans was developed using synchrotron‐radiation phase contrast imaging (SR‐PCI). On an unseen test set, the network significantly outperformed seven expert otologists/radiologists, the mean expert segmentation, and a simultaneous truth and performance level ...
Ashley Micuda   +11 more
wiley   +1 more source

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