Results 41 to 50 of about 17,452 (262)

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

Cochlear implantation in MELAS syndrome: a systematic review of audiological outcomes, surgical considerations, and clinical implications

Journal of Rare Diseases
Purpose Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome is a rare mitochondrial disorder frequently associated with sensorineural hearing loss (SNHL).
David H. Elisha, Ryan Hossain, David H. Cohen, Andrea Monterrubio, Max Zalta, Rahul Mittal, Adrien A. Eshraghi   +6 more
doaj   +1 more source

Incidence of Otolaryngological Manifestations in Individuals with Autism Spectrum Disorder: A Special Focus on Auditory Disorders

Audiology Research
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by stereotyped and repetitive behavior patterns. In addition to neurological and behavioral problems, individuals with ASD commonly experience otolaryngological comorbidities ...
Keelin McKenna, Soumil Prasad, Jaimee Cooper, Ava M. King, Shahriar Shahzeidi, Jeenu Mittal, Max Zalta, Rahul Mittal, Adrien A. Eshraghi   +8 more
doaj   +1 more source

Current Collector Engineering for New Efficient Bioresorbable Sodium‐Ion Batteries

Advanced Science, EarlyView.
A bioresorbable Na‐ion battery is proposed with Mo or Mg thin‐film current collectors for temporary implants. Mo‐based batteries exhibit superior electrochemical performance and stable cycling compared with Mg counterparts. XPS was used to investigate the Mo/Mg surface oxidation.
Bincy Lathakumary Vijayan, Eleonora Vandini, Vedi Kuyil Azhagan Muniraj, Hussien Hammoud, Oussama Jamai, Eve Djenizian, Marc Ramuz, Daniela Giuliani, Manuela Zavatti, Yann Tison, Hervé Martinez, Lucas Teolis, Esma Ismailova, David Moreau, Sébastien Maria, Thierry Djenizian   +15 more
wiley   +1 more source

Outcome of cochlear implantation in children with cochlear implantation [PDF]

European Archives of Oto-Rhino-Laryngology, 2014
Sig. (2-tailed), Exact Sig. (1-tailed)]. the above results, in agreement with Bille et al. study, indicated that children with inner ear malformation over time perform equally to children without inner ear malformation, but at a slower rate of improvement; this is in accordance with Eisenman et al.’s [3] observation that children with malformed cochlea
Dimitrios Rachovitsas, George Psillas, Stefanos Triaridis, Victor Vital, Jiannis Constantinidis   +4 more
openaire   +1 more source

Polarization Engineering in Vinylene‐Linked COFs Toward Efficient Neuromorphic Computing

Advanced Science, EarlyView.
A vinyl‐linked covalent organic framework (COF‐DIBPY) was synthesized on a conductive substrate for memristor applications. Redox reactions and bromide migration enable low‐voltage (0.5V) conductance switching with high analog on/off ratio (15.7). The device was further integrated into a speech emotion recognition system for acoustic simulation and ...
Hao Wang, Lei Zhao, Haoyuan Yao, Qiongshan Zhang, Fuzhen Xuan, Bin Zhang   +5 more
wiley   +1 more source

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

Advanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu, Bowen Yang, Cao Qi, Zhijie Zhou, Haochen Zou, Anjum Qureshi, Xiao Zhao, Ting Li, Li Gao, Ye Tao, Gang Song, Pingqiang Cai, Zheng Li, Zhiyuan Liu, Dianpeng Qi, Ting Wang, Lianhui Wang   +16 more
wiley   +1 more source

Electrode contact estimation based on preoperative versus postoperative imaging as a basis for anatomy-based fitting

Current Directions in Biomedical Engineering
Anatomy-based fitting (ABF) has the potential to lead to better outcomes than conventional clinically-based fitting (CBF). It has already been shown that anatomy-based fitting based on postoperative imaging (postopABF) can improve speech understanding ...
Schreier Andrea, Draut Sarah, Stihl Clemens, Molenda Carmen, Neuling Maike, Müller Philipp, Müller Franziska, Stöcklein Sophia, Simon Florian, Schrötzlmair Florian, Hempel John Martin, Müller Joachim, Polterauer Daniel   +12 more
doaj   +1 more source

Cochlear Implantation in Down Syndrome: Functional Outcomes, Challenges, and Management Strategies

Audiology Research
Objective: The aim was to evaluate cochlear implantation (CI) outcomes in children with Down syndrome (DS) with severe-to-profound sensorineural hearing loss (SNHL), addressing a literature gap and discussing challenges including anatomical abnormalities,
David H. Elisha, David H. Cohen, Andrea Monterrubio, Ryan Hossain, Nicholas DiStefano, Rahul Mittal, Adrien A. Eshraghi   +6 more
doaj   +1 more source

Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2

Drug Delivery, 2018
Aminoglycoside-induced hair cell (HC) loss is a major cause of hearing impairment, and the effective prevention of HC loss remains an unmet medical need.
Ao Li, Dan You, Wenyan Li, Yingjie Cui, Yingzi He, Wen Li, Yan Chen, Xiao Feng, Shan Sun, Renjie Chai, Huawei Li   +10 more
doaj   +1 more source