Results 81 to 90 of about 32,717 (310)

Access to Cochlear Implantation: Trends in Surgeon Volume and Training. [PDF]

Laryngoscope
Based on data from one cochlear implant (CI) manufacturer, a minority of surgeons (12.5%) registered 25 or more devices per year. Of those who register 25 or more devices per year, 88% have one or two years of fellowship training in otology and/or neurotology (O&N).
Espahbodi M, Trautwein P, Bestourous DE, Zwolan TA, Nassiri AM, Carlson ML, Erbele ID, Patel NS, Gurgel RK.   +8 more
europepmc   +2 more sources

Cochlear Implantation: An Overview [PDF]

Journal of Neurological Surgery Part B: Skull Base, 2018
AbstractA cochlear implant (CI) is a surgically implanted device for the treatment of severe to profound sensorineural hearing loss in children and adults. It works by transducing acoustic energy into an electrical signal, which is used to stimulate surviving spiral ganglion cells of the auditory nerve.
Eric M. Dowling, Matthew L. Carlson, Daniel Jethanamest, Nicholas L. Deep   +3 more
openaire   +3 more sources

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

Cochlear Implantation after Kidney Transplantation

International Journal of Organ Transplantation Medicine, 2012
Patients with chronic renal failure may develop sensorineural hearing loss. Cochlear implantation has rarely done after organ transplantation. Herein, we report on a 33-year-old kidney transplantation recipient who underwent cochlear implantation for her
B Hasehmi, H Bahrani Fard, Z Zandifra
doaj  

Long-Term Hearing Outcomes Following Cochlear Implantation in Far Advanced Otosclerosis. [PDF]

Otolaryngol Head Neck Surg
Abstract Objective This study aims to evaluate the long‐term auditory performance at 5 years in patients with far advanced otosclerosis (FAO) after cochlear implantation compared to controls. Study Design A retrospective cohort study. Setting This study was conducted at a single tertiary medical center.
Quatre R, Eklöf M, Wales J, Bonnard Å.
europepmc   +2 more sources

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

Advanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei, Shiwei Qiu, Xue Gao, Lu Zheng, Yijin Chen, Ying Ma, Haifeng Feng, Jinyuan Yang, Guojie Dong, Huiyi Nie, Weihao Zhao, Xiaoge Li, Guangqin Wang, Wei Xiong, Pu Dai, Yongyi Yuan   +15 more
wiley   +1 more source

Cochlear Implantation in Primrose Syndrome with a Novel ZBTB20 Gene Variant

Turkish Archives of Otorhinolaryngology, 2023
In this article, we aim to present details of the cochlear implantation procedure performed in a patient with Primrose syndrome, which is a rare genetic condition characterized by physical deformities, sensorineural hearing loss, and metabolic disorders.
Burak Anıl Tuğci, Alper Gezdirici, Can Berk Aşaroğlu, Ercan Atasoy, İbrahim Sayın, Zahide Mine Yazıcı   +5 more
doaj   +1 more source

Verbal Learning and Memory After Cochlear Implantation in Postlingually Deaf Adults: Some New Findings with the CVLT-II [PDF]

, 2018
OBJECTIVES: Despite the importance of verbal learning and memory in speech and language processing, this domain of cognitive functioning has been virtually ignored in clinical studies of hearing loss and cochlear implants in both adults and children ...
Boyce, Lauren, Broadstock, Arthur, Castellanos, Irina, Davies, Alexandra, Harris, Michael S., Hernandez, Luis R., Kronenberger, William G., Miller, Kelly, Moberly, Aaron C., Pisoni, David B., Safdar, Natalie, Vasil, Kara, Wucinich, Taylor, Xu, Huiping   +13 more
core   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source