Results 251 to 260 of about 1,072,228 (430)

Direct reprogramming of fibroblasts into spiral ganglion neurons by defined transcription factors

Cell Proliferation, Volume 58, Issue 4, April 2025.
A combination of Ascl1, Pou4f1 and Myt1l was identified to promote functional reprogramming of cochlear spiral ganglion neurons based on biochemical, electrophysiological and single‐cell transcriptomic analyses. Abstract Degeneration of the cochlear spiral ganglion neurons (SGNs) is one of the major causes of sensorineural hearing loss and ...
Yuhang Huang, Zhen Chen, Jiang Chen, Jingyue Liu, Cui Qiu, Qing Liu, Linqing Zhang, Guang‐Jie Zhu, Xiaofeng Ma, Shuohao Sun, Yun Stone Shi, Guoqiang Wan   +11 more
wiley   +1 more source

Improved optogenetic modification of spiral ganglion neurons for future optical cochlear implants. [PDF]

Theranostics
Thirumalai A, Henseler J, Enayati M, Kusch K, Hessler R, Moser T, Huet AT.   +6 more
europepmc   +1 more source

Implication of GPRASP2 in the Proliferation and Hair Cell‐Forming of Cochlear Supporting Cells

Cell Proliferation, EarlyView.
Schematic diagram of GPRASP2‐mediated SCs proliferation and HCs formation. GPRASP2 deficiency results in increased lysosomal degradation of SMO. GPRASP2‐mediated SMO/GLI1 signalling promotes SC proliferation, which contributes to HC formation. GPRASP2‐mediated SMO/β‐catenin signalling is implicated in HCs fate specification and differentiation ...
Jing Cai, Kun Huang, Wenrui Li, Tianming Wang, Shen Yue, Zhibin Chen, Guangqian Xing, Qinjun Wei, Jun Yao, Xin Cao   +9 more
wiley   +1 more source

Visual Cortical Processing in Children with Early Bilateral Cochlear Implants: A VEP Analysis. [PDF]

Children (Basel)
Badarni-Zahalka O, Dakwar-Kawar O, Adelman C, Khoury-Shoufani S, Attias J.   +4 more
europepmc   +1 more source

d‐amino acids: new functional insights

The FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni, Natasa Kustrimovic, Luciano Piubelli, Elena Rosini, Valentina Rabattoni, Silvia Sacchi   +5 more
wiley   +1 more source

A Novel Trans-Impedance Matrix (TIM) Abnormality Pattern in Cochlear Implants. [PDF]

Audiol Res
Pizzol E, Ghiselli S, Frontera P, Salsi D, Cuda D.   +4 more
europepmc   +1 more source

An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone

Journal of Anatomy, Volume 246, Issue 6, Page 1053-1074, June 2025.
Examination of an alkaptonuria body highlights the susceptibility of all cartilage types and associated perichondrium to ochronotic pigmentation and the heterogeneity of ochronotic pigment distribution both within and between tissues. In joints, calcified cartilage pigments before non‐calcified cartilage.
Juliette H. Hughes, Gemma Charlesworth, Amanda Prior, Claire M. Tierney, Paul D. Rothwell, Neil P. Thomas, Lakshminarayan R. Ranganath, James A. Gallagher, Alistair P. Bond   +8 more
wiley   +1 more source

The evolution of an “owl‐like” auditory system in harriers: Anatomical evidence

Journal of Anatomy, EarlyView.
Harriers hunt relying on sound, with an accuracy to localize sound sources comparable with owls. To assess whether they have owl‐like auditory specializations, we analyzed brain and skull structures using histology and microCT scans. Harriers possess an enlarged external acoustic meatus and significantly expanded auditory brainstem nuclei, up to 12 ...
Sara Citron, Cristian Gutierrez‐Ibanez, Aubrey Keirnan, Vera Weisbecker, Douglas Wylie, Andrew N. Iwaniuk   +5 more
wiley   +1 more source

Management of Audiological Disorders in Cochlear Implants: Outcomes in Demanding Listening Situations and Future Perspectives. [PDF]

J Clin Med
Hey M, Hoppe U.
europepmc   +1 more source

Testing of synthetic vowels in patients with 22 channel cochlear implant.

, 1994
Hiromitsu Saito, Eiji Hakuhisa, Kazuo Watanabe, Kumiko Yukawa, Tsunemasa Sato, Sotaro Funasaka   +5 more
openalex   +2 more sources