Results 91 to 100 of about 12,941 (217)

Adriamycin nephropathy induces sensorineural hearing loss via blood–labyrinth barrier breakdown in BALB/c mice

open access: yesScientific Reports
Sensorineural hearing loss (SNHL) is significantly more prevalent in individuals with chronic kidney disease (CKD) than in the general population. Although a strong independent association has been observed between kidney dysfunction and the risk of ...
Akanksha Gajbhiye   +10 more
doaj   +1 more source

The Relationship Between Blood Lipids, Coagulation Indexes, Blood Homocysteine and Sudden Deafness: A Retrospective Study and Mendelian Randomization Analysis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang   +8 more
wiley   +1 more source

An Experimental Study on the Protective Effect of Memantine in Noise‐Induced Hearing Loss

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective This study examined the potential protective effects of memantine, an N‐methyl‐D‐aspartate (NMDA) receptor antagonist, against acoustic trauma (AT) in guinea pigs, using electrophysiological and histopathological analyses. Methods Thirty guinea pigs with normal hearing were divided into six groups (n = 5 per group): Group 1 (control),
Begüm Arda   +6 more
wiley   +1 more source

Comprehensive Evaluation of AI Consent Forms in Otolaryngologic Surgery

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Surgical consent documents are frequently written at reading levels exceeding average health literacy. Large language models (LLMs) may offer a scalable approach to generating clearer, procedure‐specific consent forms. This study evaluated the clarity, clinical accuracy, and acceptability of consent forms generated by GPT‐4 and ...
Sholem Hack   +15 more
wiley   +1 more source

Speech Recognition Deficits in Presbyacusis: Links to Cortical Structural and Functional Alterations

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To characterize speech recognition in presbyacusis and its associated neurophysiological and cortical structural features, and to explore structure‐function‐behavior relationships within the presbyacusis phenotype. Methods Thirty elderly patients with presbyacusis(HI) and thirty‐three healthy young controls(NH) completed a behavioral
Xiao‐Qian Ren   +8 more
wiley   +1 more source

Corrigendum to: Transforming growth factor β1 inhibition protects from noise-induced hearing loss

open access: yesFrontiers in Aging Neuroscience, 2015
Silvia eMurillo-Cuesta   +19 more
doaj   +1 more source

Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model

open access: yesFrontiers in Neuroscience
BackgroundDespite the high prevalence of noise-induced hearing loss (NIHL), no effective treatments exist currently. Underlying mechanisms behind NIHL include elevated reactive oxygen species and inflammation, all which ultimately lead to cellular ...
Maria Fernanda Yepes   +6 more
doaj   +1 more source

Anatomical Characteristics of the Facial Nerve in Patients With Cochlear Hypoplasia

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To quantitatively characterize the spatial relationships between intratemporal facial nerve segments and key cochlear implantation (CI) landmarks in cochlear hypoplasia (CH), and to compare these features with age‐matched CI recipients with normal inner ear anatomy, thereby informing preoperative planning and facial nerve ...
Shu‐Jin Xue   +4 more
wiley   +1 more source

Association Characteristics and Potential Mechanisms of Aging, Gut Microbiota, and Hearing Loss

open access: yesIntegrative Zoology, EarlyView.
The study found that aging leads to unchanged gut microbiota alpha diversity but an increase in Bacteroidetes and a decrease in Firmicutes at the phylum level, with specific genera, species, and functional pathways co‐associated with aging and hearing loss. Through constructing a microbe‐metabolite network, it revealed the mechanism by which protective
Cheng Cheng   +7 more
wiley   +1 more source

The Moral (Un)Desirability of New Biomedical Technologies as Potential Techno‐Fixes

open access: yesBioethics, EarlyView.
ABSTRACT The techno‐fix argument, used to argue against technological interventions that address the consequences of social problems instead of their underlying causes, is increasingly invoked in biomedical discussions. However, especially in biomedicine, the techno‐fix argument remains conceptually underdeveloped.
Lieke van Kempen   +2 more
wiley   +1 more source

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