Results 91 to 100 of about 1,007,768 (261)

Injury and protection of spiral ganglion neurons

Chinese Medical Journal
. Cochlear spiral ganglion neurons (SGNs) are bipolar ganglion cells and are the first neurons in the auditory transduction pathway. They transmit complex acoustic information from hair cells to second-order sensory neurons in the cochlear nucleus for ...
Beilei Duan, Kevin A. Peng, Line Wang, Ting Gao, Xiuyuan Hao   +4 more
doaj   +1 more source

Optical Stimulation and Monitoring of the Peripheral Nervous System: Perspectives and Challenges Toward Clinical Translation

Laser &Photonics Reviews, EarlyView.
Optical neuromodulation with IR light allows stimulation of the PNS without the need for physical contact with the target nerve or without requiring any genetic modification. The clinical translation of this technique will pave the way to the development of neural interfaces for restoring sensory feedback in individuals with limb amputation.
Federica Piccirillo, Sarassunta Ucci, Anna Aliberti, Patrizio Vaiano, Alessia La Rocca, Francesca Angelone, Silvia Pascarella, Pellegrino Lippiello, Maria Concetta Miniaci, Giuseppe Prisco, Michela Russo, Francesco Amato, Deyanira Contartese, Milena Fini, Gianluca Giavaresi, Lucia Martini, Francesco Rosa, Cosimo Gentile, Emanuele Gruppioni, Armando Ricciardi, Andrea Cusano   +20 more
wiley   +1 more source

Complications related to cochlear implants: experience in Tehran [PDF]

Objective: Cochlear implantation (CI) is an effective treatment for profound deaf patients. To study the cochlear implant complications in patients at Amir Aalam Hospital.
محمدی, محمدعلی, خورسندی, محمدتقی, پیرزاده, احمد, پیرزاده, اکبر   +3 more
core  

The Incidence of Sensorineural Hearing Loss Diagnoses in People with and without Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and sensorineural hearing loss (SNHL) are both prevalent conditions among older adults. Although increasing number of studies have investigated SNHL as a risk factor for PD, it is not well known how diagnosed PD affects the likelihood of SNHL diagnosis.
Kaisa Hokkinen, Aarno Dietz, Pasi Lampela, Sirpa Hartikainen, Anna‐Maija Tolppanen   +4 more
wiley   +1 more source

Joint Risk Factor Combinations with Additive Interaction Increase the Risk of Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Combined effects of multiple risk factors on incident late‐onset Parkinson's disease (PD; LOPD) remain poorly characterized. Objective The objective of this study was to quantify the impact of joint risk exposures and estimate the contribution of potentially modifiable factors to incident LOPD risk.
Andrea Quattrone, Basilio Vescio, Fulvia Arcuri, Giuseppe Chiarella, Jolanda Buonocore, Aldo Quattrone   +5 more
wiley   +1 more source

Restoration, Not Bypass: Otoferlin Gene Therapy and a New Era in Hearing Loss Treatment

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract The FDA approval of Otarmeni, an AAV‐based gene therapy for biallelic OTOF‐associated sensorineural hearing loss, represents a conceptual shift in otology: from bypassing defective auditory physiology to restoring it. Unlike cochlear implantation, which circumvents damaged sensory structures, OTOF gene replacement targets a synaptic deficit in
Jazlyn A. Selvasingh, Justin R. Shinn
wiley   +1 more source

Formononetin ameliorates cisplatin-induced hair cell death via activation of the PI3K/AKT-Nrf2 signaling pathway

Heliyon
Cisplatin (CDDP) stands as a highly effective chemotherapeutic agent; however, its ototoxicity remains a perplexing challenge in the field. Formononetin (FMNT), a potent flavonoid isolated from Astragalus membranaceus, displays a diverse range of ...
Yimeng Li, Jingfang Wu, Huiqian Yu, Xiaoling Lu, Yusu Ni   +4 more
doaj   +1 more source

Extra-Cochlear Insertion in Cochlear Implantation: A Potentially Disastrous Condition

, 2019
OBJECTIVES: Cochlear implantation is an increasingly used technique for auditory rehabilitation of pediatric and adult population. Safe implantation is achieved in most cases; however, intraoperative complications and misplacement of the electrode are ...
Osman Kızılkılıç, Harun Cansiz, GÖZEN, Emine Deniz, Kara, Eyup, Eyup Kara, Sabri Sirolu, CANSIZ, Harun, KIZILKILIÇ, Osman, Ahmet Atas, Haydar Murat Yener, Emine Deniz Gozen, KARAMAN, Emin, Osman Kizilkilic, Yener, Haydar Murat, Fırat Tevetoğlu, Harun Cansız, Atas, Ahmet, ŞİROLU, Sabri, Firat Tevetoglu, Emin Karaman, TEVETOĞLU, Fırat, Kara, Eyyup   +21 more
core   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

COCHLEAR IMMUNE INJURY FOLLOWING DIRECT ANTIGEN CHALLENGE TO THE ENDOLYMPHATIC SAC

Nippon Jibiinkoka Gakkai Kaiho, 1993
Following direct KLH antigen challenge to the endolymphatic sac (e. sac) in guinea pigs, degeneration of the cochlea was examined histologically by light microscopy. Degeneration was seen in 21 out of 140 animals presensitized systemically from day 1 to 5 weeks post secondary KLH challenge to the e. sac.
S, Tomiyama, T, Ikezono, H, Watanabe, T, Yagi   +3 more
openaire   +3 more sources