Results 141 to 150 of about 1,007,768 (261)

Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025)

Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang, Jinqin Wei, Zhao Jiang, Yingming Luo, Yan Zhou, Jiafan Yang, Hui Cui   +6 more
wiley   +1 more source

Elucidation of the mechanism of miR‑122‑5p in mediating FOXO3 injury and apoptosis of mouse cochlear hair cells induced by hydrogen peroxide

, 2022
Jiajun Chen, Jixin Qin, Jin Liu
openalex   +2 more sources

Seronegative Propylthiouracil‐Induced Reversible Bilateral Sensory Neural Hearing Loss Without Systemic Vasculitis: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Propylthiouracil (PTU) is a thioamide drug used in the management of hyperthyroidism in selected clinical settings. While PTU is associated with well‐known adverse effects such as hepatotoxicity, agranulocytosis, and antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis, ototoxicity is an exceptionally rare complication.
Adane Alemayehu Abera, Genetu Dagnaw Alemayehu, Zelalem Tadesse Wondimu, Behaylu Tesfamaryam Hagos, Mequannet Tesfaw Addis, Mohammedsefa Arusi Dari   +5 more
wiley   +1 more source

Computational Models of the Foreign Body Response: A Focus on Biomaterial Properties

Journal of Biomedical Materials Research Part A, Volume 114, Issue 11, November 2026.
ABSTRACT The foreign body response (FBR) is the main biological process governing the long‐term performance and safety of implantable biomaterials. As the FBR is complex, multifactorial, and unfolds over extended time scales, making in vitro replication challenging, standard biological evaluation frameworks continue to rely primarily on in vivo testing
Matilde Marradi, Jennifer Riccio, Martijn van Griensven, Luca Presotto, Giuseppe Chirico, Aurélie Carlier   +5 more
wiley   +1 more source

Organ of Corti macrophages: a distinct group of cochlear macrophages with potential roles in supporting cell degeneration and survival

Frontiers in Immunology
Macrophages are the primary immune cells in the cochlea, essential for maintaining cochlear homeostasis and orchestrating inflammatory responses to pathological events.
Mengxiao Ye, Celia Zhang, Dalian Ding, Guang-Di Chen, Henry J. Adler, Rania Sharaf, Bo Hua Hu   +6 more
doaj   +1 more source

LncRNA H19 inhibits oxidative stress injury of cochlear hair cells by regulating miR-653-5p/SIRT1 axis

, 2022
Wen Qun Xie, Ting Shu, Haisen Peng, Jiali Liu, Chunhua Li, Meiqun Wang, Ping Wu, Yuehui Liu   +7 more
openalex   +1 more source

The outcome of cochlear implantation in otoferlin-related cochlear synaptopathy

, 2023
Objectives Auditory neuropathy is a hearing disorder characterized by disruption of the temporal coding of acoustic signals in the auditory fibers, which results from alterations at pre- and post-synaptic sites. The most well- known pre-synaptic form of
Michela Calegaro, Maria Dominguez-Ruiz, Ignacio del Castillo, Marica Pistello, Pietro Scimemi, Anna Chiara Mardegan, Alessandra Ferraboschi, Rosamaria Santarelli   +7 more
core  

Hearing Preservation Rates After Cochlear Implantation Using Soft Surgery Techniques

The Laryngoscope, Volume 136, Issue 11, Page 4996-5002, November 2026.
ABSTRACT Objectives To determine if hearing preservation rates after cochlear implantation varied over time with soft surgery techniques. Methods The hearing preservation rate over time in adult cochlear implant patients over 10 years was analyzed. The association between hearing preservation rate and sex, age, perioperative steroid dose, and type of ...
Tina C. Huang, Scott Lunos
wiley   +1 more source

Modifiable Risk Factors and Hearing Loss: The National Health and Nutrition Examination Survey 1999–2020

Clinical Otolaryngology, Volume 51, Issue 6, Page 929-937, November 2026.
ABSTRACT Objective To explore the associations between major modifiable risk factors and hearing loss. Methods This serial cross‐sectional study was conducted within the National Health and Nutrition Examination Survey 1999–2020 in the United States. Associations were assessed using modified Poisson regression and within‐sample population attributable ...
Yulu Zheng, Tingting Li, Zhiyuan Wu, Yahong Zhu, Zheng Guo, Xingang Li   +5 more
wiley   +1 more source

Selonsertib-Eluting Electrode Coating Attenuates Cochlear Injury Pathways [PDF]

Jacqueline M. Ogier, Lilith M. Caballero Aguilar, Michael G. Leeming, David R. Nisbet, Bryony A. Nayagam   +4 more
openalex   +1 more source